Safely Buy Savella ( Milnacipran ) from Canada Prescriptions Plus.

Indications

Savella is a pain medication used to treat chronic pain from fibromyalgia.

Milnacipran is a serotonin and norepinephrine reuptake inhibitor that prevents presynaptic reuptake of norepinephrine and serotonin without affecting other neurotransmitters such as dopamine. By increasing your availability of these two neurotransmitters, Savella reduces pain transmission which helps relieve chronic pain from fibromyalgia.

This medication has been found to be an effective treatment for fibromyalgia and chronic pain related to this condition. Savella is also generally well-tolerated and helps improve quality of life in patients.

Uses and Dosage

The dose of Savella that is prescribed will vary depending on the individual being treated. Follow all your doctor’s instructions and read packaging labels carefully.

• Swallow tablets whole
• Take with or without food, but food may improve your tolerability
• Most adults start by taking 12.5mg and follow a titration schedule to increase their dose
• Adults are recommended to take 50mg twice daily to manage fibromyalgia pain
• Doses should not exceed 200mg daily
• Do not suddenly stop taking Savella
• Check your blood pressure and heart rate regularly during treatment
• Tell your doctor if you notice any changes in your sexual function
• Store at room temperature away from moisture and heat
• Keep away from children and pets

Side Effects

Serious Side Effects

Allergic Reactions

Do not take Savella if you are allergic to milnacipran. If you develop signs of an allergic reaction, stop using this medication and contact your doctor.

Savella allergy symptoms may include:

• Hives
• Difficulty breathing
• Swelling of face, lips, tongue, or throat

Cautions

Do not take Savella if you have used an MAO inhibitor within the past 14 days. These inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine. Wait at least 5 days after stopping Savella to take an MAOI.

At the beginning of your treatment with Savella you may have suicidal thoughts, especially if you are younger than 24 years old. See your doctor regularly for the first 12 weeks.

Tell your doctor about any new or worsening symptoms such as changes in mood or behaviour, anxiety, panic attacks, insomnia, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, depressed, or have suicidal thoughts.

Avoid drinking alcohol during your treatment with Savella because it could increase your risk of damaging your liver.

To ensure your safety when taking Savella, tell your doctor if you have ever had any of the following:

• Liver disease
• Kidney disease
• Heart disease, high blood pressure
• Seizures or epilepsy
• Bleeding problems
• Low sodium levels in your blood
• Sexual problems
• If you drink alcohol
• If you take a blood thinner like warfarin

Ask your doctor about using any nonsteroidal anti-inflammatory drug (NSAID) such as aspirin, ibuprofen, or naproxen. You may bruise or bleed easily if you take these drugs with milnacipran.

Make sure that your doctor is aware if you take any stimulant medicine, opioid medication, herbal products, or any medication used to treat depression, mental illness, Parkinson’s disease, migraines, infections, or to prevent nausea and vomiting. These types of medications increase your serotonin levels and when used with milnacipran could lead to serotonin syndrome, a serious condition.

Tell your doctor if you use any medications that make you sleepy, such as cold or allergy medications, sedatives, narcotic pain medicine, sleeping pills, muscle relaxants, and medication for seizures, depression, or anxiety. These medications can increase the drowsy effects caused by milnacipran.

To ensure your safety when taking Savella, tell your doctor about all the medications you take, including over the counter medicine, vitamins, and herbal products.

Your thinking or reactions may be impaired while taking Savella. Be careful when driving or performing any tasks that require alertness, especially until you know how the medication will affect you.

Do not start or stop taking Savella if you become pregnant during treatment. Milnacipran can cause serious lung problems and other complications if taken during pregnancy, but it is not safe to suddenly stop treatment.

Ask your doctor before breastfeeding while taking this medication.

Savella is not an approved treatment for anyone younger than 18 years of age.

Form and Strength

This fibromyalgia medication is available in tablet form.

Savella tablet strengths:

• 25mg
• 50mg

Both the 25 and 50mg Savella tablets are available in quantities of 100.

FAQ

What is Savella?

How should I take Savella?

Savella should be taken twice a day with or without food after going through a titration schedule to reach the recommended dose. While milnacipran’s efficacy is not significantly altered by food, taking your doses with food could improve your tolerability of the medication. Always follow your doctor’s instructions when taking medication to ensure the best results.

Resources:

1. https://pubmed.ncbi.nlm.nih.gov/19620845/
2. https://pubmed.ncbi.nlm.nih.gov/34746490/
3. https://www.drugs.com/savella.html
4. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=8b720a1e-034b-4583-b80d-105a794cce74