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JANUVIA (SITAGLIPTIN) INDICATIONS

Januvia is an oral prescription that helps decrease blood sugar levels in adult patients with type 2 diabetes mellitus, especially after a meal. In addition, it also reduces the amount of sugar made by the body between meals by improving the levels of insulin produced by the body after a meal. Its generic name is Sitagliptin.

When Januvia is taken correctly and absorbed into the bloodstream, it works by preventing dipeptidyl peptidase-4 from breaking down the incretins. Incretins are hormones produced in the digestive tract and are responsible for improving insulin production after eating. It also decreases the amount of glucose released by the liver, lowering blood sugar levels.

Along with this oral prescription, a healthy diet and exercise should be part of an adjunct therapy to control blood sugar levels. Also, Januvia anti-diabetic medication can be used alone or in combination with some other medicine.

However, Januvia is not approved to control blood sugar levels in patients with type 1 diabetes.

JANUVIA (SITAGLIPTIN) USES AND DOSAGE

Januvia can help manage and control blood sugar levels in adults with type 2 diabetes. This oral regimen belongs to a class of medications known as dipeptidyl peptidase-4 (DPP-4) inhibitors. Most individuals require varying amounts of Januvia depending on the patient’s need. The frequency and dose are usually based on the severity of the client’s health condition, other medical problems, age, and tolerance to the medicine.

When using Januvia, read all prescription information and follow all the directions thoroughly. If you are ambiguous about how to use this antidiabetic medication, talk to your doctor or pharmacist for clarification.

The following are the Januvia recommended dosages:

The following are the directions for administering Sitagliptin:

  • Administer Januvia film-coated tablet by mouth once a day or as prescribed by your doctor
  • Take Januvia in the morning with or without regard to food
  • Take the tablet whole without splitting, chewing, or crushing it

SIDE EFFECTS OF JANUVIA (SITAGLIPTIN)

Sitagliptin may have unwanted side effects similar to other medications that may resolve over time when your body has adjusted to the medicine. The following are the common side effects of Januvia that can occur when taking Januvia:

  • Upper respiratory tract infection (URTI)
  • Nasopharyngitis
  • Headache

SERIOUS SIDE EFFECTS

  • Pancreatitis (inflammation of the pancreas)
    • Severe, persistent stomach pain with or without vomiting
  • Heart failure
  • Acute renal failure
  • Unbearable arthralgia (joint pain)

ALLERGIC REACTIONS

  • Skin rash
  • Hives
  • Skin blisters or peeling
  • Swelling (face/tongue/throat)
  • Trouble breathing or swallowing

Note that this list does not include all the drug information and health implications related to Januvia. If you experience other side effects not listed above, ask your healthcare provider for additional information.

JANUVIA (SITAGLIPTIN) CAUTIONS

When taking Januvia, warn healthcare professionals and patients about the risks of this medication, as it can cause pancreatitis, which needs to be reported immediately as this can lead to death. Make sure to be cautious for symptoms like severe, persistent abdominal pain with or without vomiting

Before taking Januvia, make sure to fully disclose your health history to your doctor, especially if you have the following medical conditions:

  • Problems in the pancreas (e.g., pancreatitis)
  • Gallstones
  • Alcohol dependence
  • High triglycerides
  • Diabetic ketoacidosis
  • Type 1 diabetes
  • Kidney problems
  • Pregnant or planning to get pregnant
  • Breastfeeding

Do not take Januvia if you are allergic to sitagliptin or other active components. Also, do not use this oral pill if you are on dialysis treatment, as it can worsen your condition. Make sure to inform your doctor if you have heart failure or kidney problems. Be vigilant to watch out for the following symptoms:

  • Increasing shortness of breath
  • Trouble breathing when lying down
  • Swelling or fluid retention (feet, ankles, or legs)
  • Rapid weight gain
  • Unusual tiredness

Stop using this medicine and contact your healthcare provider right away if you develop bullous pemphigoid, a skin blistering.

Be sure to be cautious when using Januvia with insulin or sulfonylurea, as this can increase your risk of low blood sugar (hypoglycemia). Look out for signs or symptoms like:

  • Headache
  • Irritability
  • Drowsiness
  • Hunger
  • Dizziness
  • Confusion
  • Sweating
  • Feeling jittery
  • Weakness
  • Fast heartbeat

Keep Januvia out of children’s reach and store it accordingly.

JANUVIA FORM AND STRENGTH

Januvia is available in tablet formulation with the following strengths:

  • Januvia
    • 25 mg film-coated tablet
    • 50 mg film-coated tablet
    • 100 mg film-coated tablet

FAQ

What is the difference between Metformin and Januvia the same?

No. Although both medicines can help reduce blood sugar levels, they work differently. Sitagliptin prevents DPP-4 from breaking down incretins, boosting insulin production.

Meanwhile, Metformin, a biguanide drug, decreases glucose production in the liver, lowers glucose absorption in the intestine, and enhances insulin sensitivity.

What is Januvia prescribed or used for?

It is an oral prescription that helps decrease blood sugar levels and improves glycemic control in adult patients with type 2 diabetes mellitus.

When is the best time to take Januvia?

It is ideal to establish a routine of taking Januvia at the same time every day, whether you take it in the morning or the evening. Along with diet and exercise, this oral prescription is used by adult patients with type 2 diabetes to help them better regulate their blood sugar levels. If you forget to administer your scheduled pill, take it as soon as you remember it, but make sure not to double your dose.

Will Januvia make you gain weight?

According to research, Januvia does not cause individuals to gain or lose weight. However, unusually rapid weight gain may be a sign of more severe side effects from this medication, such as heart failure or kidney problems. Call your healthcare provider immediately if you notice a sudden increase in weight.

Additional information

Brand Name:

Januvia

Scientific Name:

Sitagliptin Malate, Sitagliptin Phosphate, Sitagliptin phosphate

Other Names:

Istavel, Januvia, Sitagliptin, Xelevia

Strength(s):

25mg, 50mg, 100mg

Quantities Available:

28, 84, 100

Formulation:

Film Coated Tablet, Tablet

MedicationsCanada.com receives the above information for Januvia (Sitagliptin Phosphate) from third parties. We provide this information for general informational purposes only, and it is not intended to replace the advice of a physician. Any medical concerns should always be discussed with your doctor or a qualified health care professional.