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WELLBUTRIN XL (BUPROPION HYDROCHLORIDE EXTENDED-RELEASE) INDICATIONS

Wellbutrin XL is an antidepressant with the generic name bupropion hydrochloride. It is an extended-release pill belonging to a class of medications known as aminoketone antidepressants.

Wellbutrin XL is indicated to treat individuals with major depressive disorder (MDD). It can also be prescribed to prevent autumn-winter seasonal depression (seasonal affective disorder or SAD).

Depression is associated with poor social and occupational functioning. It is also associated with concurrent comorbidities, functional disability, and increased risk of death. Although the exact mechanism of action of Wellbutrin XL antidepressant is unknown, it is assumed that noradrenergic and dopaminergic processes play a role in its action. When this oral antidepressant is taken correctly and absorbed into the bloodstream, its mechanism may help you think more clearly, feel less anxious, and be more motivated to participate in and enjoy daily activities.

WELLBUTRIN XL (BUPROPION HYDROCHLORIDE EXTENDED-RELEASE) USES AND DOSAGE

The frequency and dosage of Wellbutrin XL depend on the severity of the client’s mental health condition, other coexisting medical problems, age, and tolerance to the medicine.

When using Wellbutrin XL antidepressant pill, make sure to read all prescription information and follow all the directions thoroughly. If you are uncertain about how to use this oral prescription, talk to your doctor or pharmacist for clarification.

Wellbutrin XL recommended doses include:

  • The usual dose for patients with MDD is 300 mg once daily. The initial daily intake is 150 mg, given as a single dose. If tolerated well, the dosage can be increased to 300 mg once daily as a target dose, not exceeding 450 mg.
  • For patients with SAD, the starting dose is 150 mg per day, given as a single dose. After one week, the dosage can be increased to 300 mg once daily if tolerated well.

The following are the directions for administering Wellbutrin XL antidepressant medicine:

  • Administer Wellbutrin XL regimen by mouth once a day, preferably in the morning or as prescribed by your doctor
  • Take Wellbutrin XL whole without chewing, crushing, or cutting the pill.
  • Administer Wellbutrin XL oral antidepressant medication without or without food. Take this pill with meals if you are feeling nauseous.
  • Do not take Wellbutrin XL medicine before sleeping, especially if you have problems falling asleep.
  • For patients with SAD, the treatment should be continued through the winter season and must be tapered and discontinued in early spring.

SIDE EFFECTS OF WELLBUTRIN XL (BUPROPION HYDROCHLORIDE EXTENDED-RELEASE)

Bupropion hydrochloride may have unwanted side effects similar to other medicines that may resolve over time when your body has adjusted to it.

The following are the common side effects of Wellbutrin XL that can occur after taking Wellbutrin XL antidepressant pill:

For MDD:

  • Weight loss
  • Loss of appetite
  • Dry mouth
  • Skin rash
  • Sweating
  • Ringing in the ears
  • Shakiness
  • Abdominal pain
  • Agitation
  • Anxiety
  • Dizziness
  • Trouble sleeping
  • Muscle pain
  • Nausea
  • Fast heartbeat
  • Sore throat
  • Urinating more often

For SAD:

  • Weight loss
  • Constipation
  • Gas

SERIOUS SIDE EFFECTS

  • Increased suicidal thoughts
  • Attempts to harm oneself
  • Agitation
  • Panic attacks
  • Hyperactivity
  • Impulsive behavior
  • Unusual changes in behavior or mood
  • New or worsening depression, anxiety, or irritability

ALLERGIC REACTIONS

  • Skin rash
  • Hives
  • Skin blisters or peeling
  • Swelling (face/tongue/throat)
  • Trouble breathing or swallowing

Bear in mind that this list does not include all the drug information and health implications related to Wellbutrin XL antidepressant pill. If you experience other side effects not listed above, ask your healthcare provider for additional information.

WELLBUTRIN XL (BUPROPION HYDROCHLORIDE EXTENDED-RELEASE) CAUTIONS

Healthcare professionals and patients are cautioned about the risks and benefits of treatment when taking Wellbutrin XL, as this can increase suicidal thoughts or actions within the first few months of treatment. Make sure to pay close attention and call your doctor right away if you notice sudden changes in mood, behaviors, thoughts, or feelings.

  • Delusions
  • Hallucinations
  • Paranoia
  • Feeling confused

Before using Wellbutrin XL oral antidepressant medication, make sure to fully disclose your health history to your doctor, especially if you have the following medical conditions:

  • Liver disease (e.g., cirrhosis)
  • Kidney problems
  • Eating disorder (e.g., anorexia nervosa or bulimia)
  • Head injury
  • History or currently have seizures or convulsions
  • Tumors in the nervous system
  • Heart attack
  • Heart problems
  • High blood pressure (hypertension)
  • Diabetes
  • Drink alcohol regularly/excessively
  • Pregnant or trying to become pregnant
  • Breastfeeding

Do not take Wellbutrin XL antidepressant if you are allergic to bupropion hydrochloride or any of its other components.Avoid using Wellbutrin XL oral pill if you have the following:

  • Seizure disorder
  • Using sedatives and Zyban (medicine to help people stop smoking)
  • Drink a lot of alcohol and suddenly stop drinking
  • Taking monoamine oxidase inhibitor (MAOI) (e.g., Nardil, Parnate, Marplan)
  • Eating disorders

If you want to stop drinking alcohol, make sure to talk to your doctor because abrupt discontinuation may increase your chance of developing seizures.

Avoid doing tasks that need alertness, such as driving, operating heavy machinery, or doing other dangerous activities, as Wellbutrin XL medicine may increase your risk of injuries or mishaps.

Keep Wellbutrin XL oral antidepressant out of reach of the children and store them properly to preserve their effectiveness.

WELLBUTRIN XL (BUPROPION HYDROCHLORIDE EXTENDED-RELEASE) FORM AND STRENGTH

Wellbutrin XL medicine is available in tablet formulation with the following strengths:

  • Wellbutrin XL
    • 150 mg extended-release tablet
    • 300 mg extended-release tablet
  • Generic Wellbutrin XL (Bupropion hydrochloride)
    • 150 mg extended-release tablet
    • 300 mg extended-release tablet
    • 450 mg extended-release tablet

FAQ

What does Wellbutrin XL do?

Wellbutrin XL antidepressant medication helps treat patients with major depressive disorder and prevents autumn-winter seasonal depression (seasonal affective disorder or SAD).

What are the side effects of Wellbutrin XL?

The following are the common side effects of Wellbutrin XL. For MDD:

  • Weight loss
  • Loss of appetite
  • Dry mouth
  • Skin rash
  • Sweating
  • Ringing in the ears
  • Shakiness
  • Abdominal pain
  • Agitation
  • Anxiety
  • Dizziness
  • Trouble sleeping
  • Muscle pain
  • Nausea
  • Fast heartbeat
  • Sore throat
  • Urinating more often

For SAD:

  • Weight loss
  • Constipation
  • Gas

Is Wellbutrin XL a good antidepressant pill?

Yes, Wellbutrin XL aminoketone antidepressant medication is a highly effective pill in treating depression.

Additional information

Brand Name:

Wellbutrin XL

Scientific Name:

Bupropion, Bupropion XL

Other Names:

Bupropion XL, Wellbutrin XL

Strength(s):

150mg, 300mg

Quantities Available:

90, 180

Formulation:

ER Tablet, Tablet

MedicationsCanada.com receives the above information for Wellbutrin XL (Bupropion) from third parties. We provide this information for general informational purposes only, and it is not intended to replace the advice of a physician. Any medical concerns should always be discussed with your doctor or a qualified health care professional.