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FARXIGA (DAPAGLIFLOZIN) INDICATIONS

Farxiga is an oral prescription indicated for patients for adults with type 2 diabetes mellitus (DM). It is an adjunct therapy to diet and exercise to control blood sugar levels. In addition, this oral antidiabetic medication can help reduce the risk of fatal cardiovascular death and the possibility of hospitalization for heart failure.

Farxiga’s generic name is dapagliflozin which belongs to a class of medicines known as sodium-glucose co-transporter 2 (SGLT2) inhibitors.

Usually, the body produces insulin when eating, which helps in the transport of glucose from the bloodstream into the cells. After transportation, glucose is then converted to energy.

Individuals with type 2 DM are usually resistant to insulin at first and may progress to stopping the production of insulin later on. When there is no insulin, the cells cannot absorb glucose, causing high blood sugar levels (hyperglycemia).

When Farxiga is taken correctly and absorbed into the bloodstream, it blocks SGLT2. SGLT2 is the primary transporter responsible for the reabsorption of filtered glucosefrom the small network of tubules in the kidney which filters blood to create urine.

When Farxiga antidiabetic medication inhibits SGLT2, it enables you to urinate excess glucose from your body by decreasing the reabsorption of filtered glucose and reducing the renal glucose threshold.

In addition, Farxiga prescription reduces sodium reabsorption and increases sodium to the distal tubule. As a result, it decreases the strain put on the heart when it relaxes and fills with blood, and also reduces the pressure with which the heart ejects the blood to the rest of the body.

FARXIGA (DAPAGLIFLOZIN) USES AND DOSAGE

Farxiga’s dosage and frequency varies depending on the needs of the patient. It is usually based on the severity of the client’s existing health problem, renal function, and response to the regimen.

When using Farxiga, read all prescription information and follow all the directions thoroughly. If you are not sure about how to use this oral prescription, talk to your doctor or pharmacist for clarification.

The first indication for Farxiga is to improve blood sugar levels in patients with DM. The typical initial intake to decrease blood sugar levels is 5 mg once a day. This dosage may be increased to 10 mg if additional glycemic control is needed.

The second indication for Farxiga is to decrease the risk of fatal cardiovascular diseases and the possibility of hospitalization for heart failure. The recommended dose is 10 mg once a day or as prescribed by your doctor.

The following are the directions for administering dapagliflozin:

  • Administer Farxiga film-coated tablet orally once a day or as prescribed by your doctor.
  • Take this prescription with or without food.

SIDE EFFECTS OF FARXIGA (DAPAGLIFLOZIN)

Dapagliflozin may have unwanted side effects similar to other medications that may resolve over time when your body has adjusted to the medicine.

The following are common side effects of Farxiga: 

  • Vaginal yeast infections
  • Stuffy or runny nose
  • Sore throat
  • Changes in urination (e.g., urgent need to urinate more often, in larger amounts, or at night)

SERIOUS SIDE EFFECTS

  • Dehydration
    • Dizzy
    • Fainting
    • Light-headed
    • Weakness
    • Orthostatic hypotension (feeling of dizziness when standing)
  • Vaginal yeast infections
    • Vaginal odor
    • White or yellowish vaginal discharge
    • Vaginal itching
  • Yeast infections of the penis
    • Redness
    • Itching
    • Swelling
    • Rash of the penis
    • Foul-smelling discharge
    • Pain in the skin around the penis
    • Feel dizzy
    • Fainting
  • Severe urinary tract infection (UTI)
    • A burning feeling when urinating
    • A need to urinate often
    • The need to urinate right away
    • Pain in the lower abdomen (pelvis)
    • Blood in the urine
    • Fever
    • Back pain
    • Nausea
    • Vomiting
  • Low blood sugar levels (hypoglycemia)
    • Headache
    • Weakness
    • Confusion
    • Feeling jittery
    • Drowsiness
    • Dizziness
    • Irritability
    • Sweating
    • Hunger
    • Fast heartbeat
  • Severe bacterial infection damaging the tissue under the skin (necrotizing fasciitis)
    • Fever
    • Feeling very weak
    • Tired
    • Malaise
    • Pain or tenderness
    • Swelling o redness of skin (erythema)
  • Ketoacidosis (high ketones in the blood or urine)
    • Nausea
    • Tiredness
    • Vomiting
    • Trouble breathing
    • Abdominal pain

ALLERGIC REACTIONS

  • Skin rash
  • Hives (raised red patches on the skin)
  • Itching
  • Chest pain
  • Swelling (face/tongue/throat)
  • Trouble breathing
  • Dizziness

This is not a complete list of all the potential health risks associated with this antidiabetic medication. Call your healthcare provider for additional information about other side effects not listed above.

FARXIGA (DAPAGLIFLOZIN) CAUTIONS

Taking Farxiga antidiabetic medication cautions healthcare providers and patients about the risks of this medication, as this can cause dehydration, especially for individuals who are as follows:

  • Using medicines to reduce blood pressure (e.g., water pills or diuretics)
  • People aged 65 years or older
  • On a low sodium diet
  • Have reduced kidney function or disease

If you suspect you may have a genital yeast infection, tell your provider right away so they can treat them with appropriate antifungal medications.

Before taking Farxiga oral antidiabetic medication, fully disclose your health history to your doctor, especially if you have the following medical conditions:

  • Type 1 diabetes
  • Have had diabetic ketoacidosis
  • Kidney or liver conditions
  • Will undergo a surgery
  • Have changes in your diet or are eating less
  • Problems urinating or history of urinary tract infections (UTI)
  • Problems in the pancreas (e.g., pancreatitis)
  • Drinkalcohol frequently or excessively (binge drinking)
  • Pregnant or planning to get pregnant
  • Breastfeeding

Do not take Farxiga medication if you are allergic to dapagliflozin or any of its other components. Look out for hypersensitivity reactions when using this antidiabetic medicine.

Do not use Farxiga oral pill if you are on dialysis treatment or have severe kidney problems, as this can worsen your condition.

Be watchful for signs and symptoms associated with ketoacidosis, especially in diabetic individuals who were sick or had surgery during treatment with Farxiga, as ketoacidosis is a life-threatening condition that can lead to death.

Dapaglifozin may cause harm to your unborn baby if you take it during your second or third trimester of pregnancy. Ask your doctor what medication is best to control your blood sugar during pregnancy. Keep Farxiga oral antidiabetic medication out of children’s reach and store it accordingly.

FARXIGA (DAPAGLIFLOZIN) FORM AND STRENGTH

Farxiga medicine is available in tablet formulation with the following strengths:

  • Farxiga
    • 5 mg film-coated tablet
    • 10 mg film-coated tablet
  • Farxiga generic (dapaglizofin)
    • 5 mg film-coated tablet
    • 10 mg film-coated tablet

FAQ

What is Farxiga used for?

Farxiga oral antidiabetic is used for adult individuals with type 2 diabetes mellitus (DM) as an adjunct therapy to diet and exercise to control blood sugar levels. In addition, this prescription can help reduce the possibility of cardiovascular death and the possibility of hospitalization for heart failure.

What are the effects of Farxiga on the kidneys?

Farxiga medication helps your kidneys get rid of excess blood sugar in the body by decreasing the reabsorption of filtered glucose and reducing the renal glucose threshold.

Additional information

Brand Name:

Farxiga

Scientific Name:

Dapagliflozin

Other Names:

Dapagliflozin, Forxiga

Strength(s):

5mg, 10mg

Quantities Available:

56, 84, 100, 168

Formulation:

Film Coated Tablet, Tablet

MedicationsCanada.com receives the above information for Farxiga (Dapagliflozin) from third parties. We provide this information for general informational purposes only, and it is not intended to replace the advice of a physician. Any medical concerns should always be discussed with your doctor or a qualified health care professional.