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About Zofran ODT (Ondansetron ODT)

Zofran ODT and Ondansetron (generic for Zofran ODT) is an antiemetic medication for individuals fighting cancer, preventing nausea and vomiting. Its generic name is ondansetron. It is available in an orally disintegrating tablet with a strength of Zofran ODT 4 mg and Zofran ODT 8 mg.

Uses of Zofran ODT

Chemotherapy and radiation treatments can cause nausea and vomiting. Chemotherapy and radiation agents are meant to destroy cancer cells. However, some of the normal cells in the gastrointestinal tract are affected, causing the body to become nauseous. The immune system detects it as toxic drugs, and being nauseous is the typical immune response trying to eliminate of these toxins.

This oral medication is used to block vomit signals. When this drug is taken correctly and absorbed into the bloodstream, it works as a serotonin blocker. Serotonin (5-HT3) is a chemical messenger that sends messages to your vomit center when triggered by chemo drugs or radiation treatment. By suppressing these signals, the brain will not detect those cytotoxic substances. As a result, you will not feel nauseous or vomit.

• What is Zofran ODT used for? 

This medication helps prevent nausea and vomiting from cancer drugs and radiation treatment. Additionally, this medicine inhibits nausea and vomiting after the surgical procedure due to the effects of anesthesia.

• What is Zofran ODT 4mg used for?

It is given to children 4-11 years old to prevent nausea and vomiting due to chemotherapy.

• What is Zofran ODT 8 mg used for?

It is given to adults and individuals 12 to 17 years old to prevent nausea and vomiting due to chemotherapy and radiation treatment.

Side Effects of Zofran ODT (Ondansetron ODT)

The following are the common side effects of Zofran ODT and may resolve with time without medical intervention:

• Headache
• Dizziness
• Drowsiness
• Body discomfort
• Fatigue
• Stomach upset
• Constipation or diarrhea

However, it is best to notify your healthcare professional immediately if Zofran’s ODT side effects worsen over time. Doing so will prevent the following adverse effects of this medication, which can be fatal if not treated immediately.

• Abnormal heart rhythm
• Palpitations
• Allergic reactions:
• Rashes
• Hives
• Swelling of the face and lips
• Throat stiffness
• Trouble breathing

Remember that this is not the complete list of the potential ondansetron ODT side effects. Discuss with your health professional for other unwanted side effects.

Dosage of Zofran ODT (Ondansetron ODT)

The Zofran ODT dosage and frequency differ from person to person. It will generally depend on the extent of the patient’s condition, age, and tolerance to the medication.

The usual adult dosage to treat severe nausea and vomiting from chemotherapy is a single 24 mg dose administered 30 minutes before beginning the administration of chemotherapy. Meanwhile, Zofran ODT 8 mg is given to treat moderate nausea and vomiting from chemo drugs. Another 8 mg pill is administered eight hours after the first dose and should continue taking this drug twice daily for one day after completing chemotherapy.

An 8 mg pill is given to prevent nausea and vomiting one to two hours before radiation therapy. A similar intake can be given every eight hours after the first dose for one to two days after completing radiation therapy or as prescribed by your doctor.

The suggested dose to prevent nausea and vomiting after a surgical procedure is 16 mg. It is given to adult patients one hour before the induction of anesthesia.

The pediatric Zofran ODT dose depends on their age group. The recommended dose for children ages 12 to 17 is given 8 mg 30 minutes before the start of chemotherapy. An identical dosage is given eight hours after the first dose. Continue taking this drug twice daily for one to two days after chemotherapy.

Young individuals aged 4 to 11 are given Zofran ODT 4mg given 30 minutes before the start of chemotherapy. A subsequent 4 mg intake is administered four and eight hours after the first dose. It should be taken thrice daily for one to two days after completing chemotherapy.

The doses of this antiemetic medication should not be altered without the proper assessment of your healthcare provider, as this can make you more prone to developing its side effects. If you fail to administer this oral pill, do not double your doses.

Warnings About Zofran ODT

Here are some of the Zofran-ODT warnings that should not be neglected:

Before using this medication, inform your doctor about your medical history, especially if you have Irregular heart rate, liver problems, or stomach conditions to know if this drug is appropriate for you and to prevent aggravating your current health condition.

Do not use this medicine if you have a known allergy to ondansetron or other ingredients. This antiemetic drug may cause allergic reactions. When you experience allergic symptoms, it is best to seek medical help as soon as possible.

This medication can cause irregular heart rate (QT prolongation), which can be fatal and needs medical attention right away. Low levels of potassium and magnesium can increase the risk of QT prolongation. Use caution when using this drug with diuretics or water pills.

Another ondansetron ODT warning is to avoid driving or operating machines, as this medication can cause drowsiness or dizziness. If you experience these symptoms, make sure to get up slowly when rising from a sitting or lying position.

Use caution when using this drug in patients with phenylketonuria (PKU) because it contains aspartame.

During pregnancy, this drug should only be used if needed. Make sure to review the risks and benefits of this regimen with your doctor.

Keep and store ondansetron accordingly, away from the reach of the children.

FAQs Related to Zofran ODT

How to take Zofran ODT?

Before using this antiemetic drug, make sure to read all medication instructions and information provided in the patient leaflet. Use the medication precisely as instructed and consult your healthcare provider, especially if you are unsure how to administer this orally disintegrating tablet.

It should be noted that the first dose of this medication is administered before the procedure, chemotherapy, or radiation treatment.

Place the on top of the tongue. Let it melt or dissolve on its own. Do not chew or swallow it. After it dissolves, you can drink liquids. Make sure to administer this drug with dry hands.

How much Zofran ODT can I take to prevent nausea and vomiting?

The dosage and frequency of taking this pill depend on your doctor’s recommendation and your condition. You can check our dosing guide for your reference. However, it is best to follow the instructions of your doctor.

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Price of Zofran ODT (Ondansetron ODT)

The price of Zofran ODT markedly more reasonable than in other countries.

Given how well this medication functions, the price will vary depending on the dosage and how much you buy. We genuinely believe that our customers should only receive the best. Thus, we promise and certify to provide top-notch medications at a reasonable cost.

Zofran ODT 4mg price and Zofran ODT 8mg price are a bit pricey. You can get generic Zofran ODT price at a fair cost. For your reference, you can check our pricing information for this drug at the top of this description.