Noxafil (Posaconazole)

Noxafil (Posaconazole) is a prescription medication used to treat or prevent fungal infections from spreading throughout the body. This drug is used in patients with weak immune systems resulting from certain treatments like chemotherapy or stem cell transplantation. People with weak immune systems have difficulty fighting off fungal spores and preventing them from becoming infections. Noxafil is also used to treat fungal infections in patients who do not respond or cannot tolerate other medicines used to treat such fungal infections. The active ingredient in Noxafil is Posaconazole. Posaconazole belongs to a class of medications called azole antifungals. It works by killing or slowing the growth of the fungi that causes infection.

Manufacturer Information

Get medical help immediately if you have any of these signs or an allergic reaction while taking Noxafil. The most common side effects of Noxafil may include the following:
• Cough;
• Diarrhea;
• Dizziness;
• Headache;
• Low potassium;
• Nausea;
• Sleeping difficulties;
• Stomach upset;
• Vomiting

Contact your doctor right away if you have any of the severe side effects, including:
• Constipation;
• Fast or pounding heartbeat;
• Increased thirst or urination;
• Irregular heartbeat;
• Numbness;
• Shortness of breath;
• Sudden dizziness;
• Swelling in an arm or leg;
• Yellowing of skin or eyes

These are not all of the side effects of Noxafil. Always contact your doctor if you notice any unusual symptoms.

You should not take Noxafil if you are allergic to Posaconazole or any ingredient in Noxafil. Before you start taking this medication, tell your doctor about your medical history, especially if you:
• Are breastfeeding or plan to breastfeed;
• Are pregnant or plan to become pregnant;
• Have an abnormal heart rhythm tracing (ECG);
• Have an allergic reaction to other antifungal medications;
• Have an electrolyte imbalance;
• Have blood circulation problems;
• Have heart problems;
• Have kidney disease;
• Have liver disease

Tell your doctor about all your medications, including prescription, OTC, herbal supplements, and vitamins. There may be drug interactions between Noxafil and quinidine, sirolimus, pimozide, midazolam, lovastatin, ergotamine, etc. Avoid rifampicin, phenytoin, efavirenz, omeprazole ciclosporin, verapamil or digoxin with Noxafil. Tell your doctor if you are pregnant or planning to become pregnant. Noxafil can harm an unborn baby. Women of childbearing potential should use effective contraception while taking this drug. Noxafil is excreted in breast milk. Inform your doctor if you are breastfeeding or planning to breastfeed. Take Noxafil precisely as prescribed by your doctor. Your dose and length of treatment will depend on the type of infection you have. Take this drug during or immediately after food or a nutritional drink. Swallow the tablet whole. Do not crush, chew, or break it. Tell your doctor if you cannot swallow the tablet whole. Keep using Noxafil even if your symptoms improve. Skipping doses could make your infection resistant to medication. Posaconazole is for treating fungal infections. This drug will not treat a viral infection like the flu or common cold. Contact your doctor if you vomit or have diarrhea while using this drug. Noxafil may not work well during this time. Store this medicine at room temperature, away from moisture and heat. Keep Noxafil out of the sight and reach of children.

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