Safely Buy Savaysa ( Edoxaban Tosilate ) from Canada Prescriptions Plus.

Indications

Savaysa is an anticoagulant medication used to reduce the risk of stroke and blood clots in patients with atrial fibrillation (AFib) that is not caused by a heart valve problem. This medication also treats blood clots in your legs associated with deep vein thrombosis (DVT) to prevent pulmonary embolism (PE).

Edoxaban tosilate is a factor Xa inhibitor that reduces activities that contribute to blood clotting such as platelet aggregation caused by prothrombinase. These inhibitory actions allow Savaysa to prevent blood clotting and strokes by reducing the production of factors that lead to the onset of these conditions.

Dosage and Administration

The dose of Savaysa that is prescribed will vary depending on the individual and type of thrombotic condition being treated. Follow all directions offered by your healthcare provider and read packaging instructions carefully to ensure the best therapeutic results during treatment. Do not stop taking Savaysa or change your dose unless directed to do so by your healthcare provider.

• Swallow tablet whole
• Take with or without food
• Do not take a double dose of Savaysa to make up for a missed dose
• Temporarily stop using Savaysa at least 24 hours before receiving surgery
• Store at room temperature away from children and pets

To treat nonvalvular AFib:

• Most adults take 60mg once a day
• Patients with reduced creatinine clearance should take 30mg once daily

Treatment for DVT and PE:

• After 5 to 10 days of initial treatment with a parenteral anticoagulant, adults should take 60mg of Savaysa once a day
• Patients with reduced creatinine clearance should only take 30mg once a day

Transitioning from other anticoagulant medications to Savaysa:

• Wait for your blood clotting test to be less than or equal to 2.5 after using warfarin before taking Savaysa
• For other oral anticoagulants, take Savaysa at the same time as your next scheduled dose
• Start Savaysa at the time of your next dose after stopping a low molecular weight heparin
• Start Savaysa four hours after stopping using an unfractionated heparin infusion

Side Effects

Savaysa may cause some side effects to develop while inhibiting processes in your blood that lead to clots. Speak with your healthcare provider to learn more about any symptoms that you may experience when taking this medication.

Common Savaysa side effects:

• Bleeding
• Low red blood cell count (pale skin, unusual tiredness, light-headed feeling, shortness of breath, cold hands and feet)

Serious Side Effects

Some more serious adverse reactions may occur when taking this medication. Stop using Savaysa and contact your doctor right away if you develop any of the following symptoms:

• Easy bruising or bleeding
• Pain, swelling, or drainage from a wound or injection site
• Bleeding from a wound or injection
• Uncontrollable bleeding
• Headaches, dizziness, weakness, feeling faint
• Urine that is pink, red, or brown
• Bloody or tarry stools, coughing blood, vomit that looks like coffee grounds

Seek immediate medical attention if you develop any signs of a spinal blood clot which include back pain, lower body numbness or muscle weakness, loss of bladder or bowel control.

Allergic Reactions

Do not use Savaysa if you are allergic to edoxaban tosilate. If you develop signs of an allergic reaction during treatment, stop using this medication and call your doctor.

Savaysa allergy symptoms may include:

• Hives
• Difficulty breathing
• Swelling of face, lips, tongue, or throat

Cautions

Savaysa should not be used by anyone with nonvalvular atrial fibrillation whose creatinine clearance is greater than 95ml/min.

Do not suddenly stop taking your doses of Savaysa or discontinue treatment earlier than recommended because your risk of developing ischemic events will increase.

Do not take Savaysa if you have moderate to severe narrowing of your mitral valve.

Do not use Savaysa if you have antiphospholipid syndrome with a history of blood clots, especially if you have positive triple antibody tests.

Savaysa users who receive anesthesia or undergo a spinal puncture may experience an epidural or spinal hematoma which may cause long-term or permanent paralysis. Your risk may be greater if you have any of the following:

• Genetic spinal defect
• Spinal catheter
• History of spinal surgery or repeated spinal taps
• Recent spinal tap or epidural anesthesia
• If you are taking a nonsteroidal anti-inflammatory
• If you use other blood clot medications

Savaysa can increase your bleeding. Call your healthcare provider right away if you notice any of the following:

• Bleeding gums
• Nosebleeds
• Heavy menstrual periods
• Abnormal vaginal bleeding
• Blood in your urine or stools
• Coughing blood
• Vomit that looks like coffee grounds

Your risk of bleeding may be increased if you have any of the following:

• Inherited bleeding disorder or one that is caused by a disease
• Hemorrhagic stroke
• Uncontrolled high blood pressure
• Stomach or intestinal bleeding or ulcer
• If you take certain medicines that can cause bleeding like aspirin, enoxaparin, heparin, warfarin, or some types of antidepressants

Avoid participating in any activities that can increase your risk of injury or bleeding during treatment with Savaysa because it can cause you to bleed more easily. You should also try to avoid causing yourself to bleed when shaving or brushing your teeth.

To ensure your safety when taking Savaysa, tell your doctor if you have ever had any of the following:

• Artificial heart valve
• Bleeding problems
• Liver or kidney disease

Tell your doctor if you are pregnant or as soon as you become pregnant while taking Savaysa. This medication may cause bleeding issues in you and your child if taken during pregnancy.

Do not breastfeed during treatment with Savaysa.

Some drugs can interact with Savaysa and cause adverse reactions. Tell your healthcare provider about all the medications that you take to avoid this, including over the counter medicines but especially any of the following:

• Other blood clotting medication
• Blood thinners (heparin, warfarin, and others)
• Nonsteroidal anti-inflammatory drugs (aspirin, ibuprofen, naproxen, and more)
• Antidepressant medications (citalopram, duloxetine, fluoxetine, sertraline, and others)
• Rifampin

Form and Strength

This anticoagulant medication is available in film-coated tablet form.

Savaysa tablet strengths:

• 30mg
• 60mg

The 30 and 60mg Savaysa tablets are both available in quantities of 84.

FAQ

Are there any foods I can’t eat while I am taking Savaysa?

There are no restricted foods during treatment with Savaysa. You can eat your normal diet or follow advice from your healthcare provider. This medication can also be taken with or without food, making it convenient to take your daily doses.

When should I take Savaysa each day?

You can take your daily dose of Savaysa at any time of day that is most convenient for you and your schedule. Ensure that you take your dose at the same time each day for the most effective results. You can also take your dose without regard to meals.

Resources:

1. https://www.drugs.com/savaysa.html
2. https://savaysa.com/
3. https://daiichisankyo.us/prescribing-information-portlet/getPIContent?productName=Savaysa&inline=true
4. https://daiichisankyo.us/prescribing-information-portlet/getPIContent?productName=Savaysa%20Med&inline=true