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What is Linzess Used For?

Linzess (linaclotide) is used to treat adults with irritable bowel syndrome with constipation (IBS-C) and chronic idiopathic constipation (CIC), who have not responded to treatments such as fiber supplements and laxatives. 

What Are Linzess Side Effects?

Most medications may cause some unwanted side effects along with the needed effects. Some may simply go away after the body has adjusted to the medicine. But there are some that need to be reported to the healthcare provider or need immediate medical attention. 

Here are the common side effects of Linzess: 

-Diarrhea 

-Flatulence (gas) 

-Pain/discomfort in the stomach 

-Bloating and a feeling of pressure or fullness in the stomach (distention) 

If the symptoms listed above persist and become bothersome or worse, contact your doctor. 

The following are the serious side effects of Linzess: 

–Allergic reaction is shown by rashes, itchiness, swelling of the face, lips, tongue, or throat, severe dizziness, and difficulty breathing.  

-Severe diarrhea 

-Diarrhea with dizziness or lightheadedness 

-Black (look like tar) or bloody stools 

If you experience any conditions and symptoms listed above, contact your healthcare provider right away or seek immediate medical help. 

Warnings and Interactions – Linzess 

Do not use Linzess if you are allergic to its active and inactive ingredients.

You should not take this medication if you have bowel obstruction (a blockage in your intestines).

Do not give Linzess to children and adolescents without a doctor’s advice. The effectiveness and safety of this medication in patients below 18 years of age have not been established. 

Inform your doctor if you are pregnant at the moment or planning to get pregnant. It is unknown whether Linzess will harm an unborn baby or not.

Linzess for constipation

Constipation is a condition in which bowel movements become less frequent three or fewer times a week, and stools are hard to pass. To treat constipation in adults associated with IBS and CIC, Linzess is prescribed.

Linzess works by binding to GC-C receptors in the intestinal epithelium which leads to the activation of Guanylate Cyclase-C (GC-C). This results in increased release of intestinal fluid and speeded GI movement, as well as decreasing the amount of pain in the abdomen and digestive tract, or visceral pain. These actions help in softening the stool, having regular bowel movements, and relieving abdominal pain. 

Linzess dosage 

This medication comes in a capsule form and is available in three different strengths: 72 mcg, 145 mcg, and 290 mcg. 

For the treatment of irritable bowel syndrome with constipation, the recommended dose is Linzess 145 mcg taken by mouth once daily. 

For the treatment of chronic idiopathic constipation, the recommended dose is Linzess 145 mcg taken by mouth once daily. Linzess 75 mcg orally once daily may be taken based on individual tolerability and characteristics. 

Directions

Take this medication exactly as prescribed by your healthcare provider. Read the medication guides or instruction sheets carefully and follow all the directions on the prescription label.

Take this medication orally (by mouth) on an empty stomach, at least 30 minutes before having your first meal of the day. Swallow the capsules whole and do not chew, crush or break them. 

If it is hard for you to swallow the capsule whole, you may open it and sprinkle the contents into a spoonful of apple sauce or an ounce of water. If needed, you may also administer it with water through a nasogastric or gastrostomy tube. 

Place a teaspoonful of applesauce into a clean container for oral administration with applesauce. Open the capsule and drizzle the contents on applesauce. Consume the entire mixture without chewing the beads. Avoid storing the mixture for later use. 

Pour around 30 ml of lukewarm bottled water into a clean glass or cup for oral administration with water. Open the capsule and drizzle the contents (beads) into the water. Swirl the mixture of beads and water gently for 20 seconds, then immediately swallow the entire mixture. Add another 30 ml of water to any beads left in the cup, then swirl for 20 seconds and swallow. Avoid storing the mixture for later use.

FAQs About Linzess

-What is Linzess?

Linzess is a prescription medicine that contains an active ingredient called linaclotide. This medication belongs to a class of drugs called IBS Agents; Gastrointestinal, Guanylate Cyclase-C Agonists. 

-Is Linzess for weight loss?

Weight loss is not the approved indication of Linzess and it is not known if this medication is safe and effective for weight loss. However, weight changes may happen when taking Linzess. There have been reports of weight loss and weight gain with Lizness use. The effect of Lizness on weight is not clearly understood. 

-How long does it take Linzess to take effect?

-Linzess usually starts to work in about a week. Improvements in your symptoms such as abdominal pain and bloating and regular bowel movement should be seen within 4-12 weeks. Daily use of this medication will improve your symptoms over time.  

How Much Does Linzess Cost?

When you buy Linzess online, the costs vary based on the dosage, quantity, and site that you visit. You may check the available prices from this page. See the top of this page for the pricing information.