Clindoxyl Gel (Clindamycin/Benzoyl Peroxide) is a topical medication typically used to treat acne. The active ingredients, benzoyl peroxide and clindamycin, have many antibiotic properties, as well as a mild drying effect that allows excess oils and dirt to be easily washed away from the skin. Benzoyl peroxide releases oxygen, which oxidise bacterial proteins in the sebaceous follicles. This reduces sebum production, reduces the number of bacteria in the area, and prevents clogged pores. Clindamycin acts as a bacteriostatic agent that interferes with the 50S subunit of the C. Acnes ribosome, which inhibits bacterial protein synthesis, effectively killing the bacteria and preventing it from replicating. You should not use Clindoxyl Gel if you have very sensitive skin, or if you are allergic to benzoyl peroxide or clindamycin. Before using Clindoxyl Gel, make sure this medication is right for you by applying a very small amount of the medication to one or two small affected areas every day for three days in a row. If there is no reaction, begin using the full prescribed amount. Do not take by the mouth. Topical medication is for use only on skin. Do not use on open wounds, or on sunburned, windburned, dry, or irritated skin. Avoid using Clindoxyl Gel on areas of eczema. Use this medication as directed. Common side effects of using Clindoxyl Gel include mild stinging or burning, itchy or tingly feeling, skin dryness, peeling, or flaking, or redness or other irritation. Stop using Clindoxyl Gel and call your doctor immediately if you experience severe itching or burning, severe stinging or redness, swelling, or severe peeling. If you experience signs of any allergic reaction, or other serious side effects, seek emergency medical attention. Allergic reactions can occur anywhere from just a few minutes after application, of within a day or longer afterward.
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