Bosulif (Bosutinib Monohydrate) is used to treat a type of blood cancer called Philadelphia-chromosome positive chronic myelogenous leukemia (CML). Bosulif is typically used when other treatments have failed. Bosulif works by inhibiting a specific enzyme that is needed by CML to function properly. It also blocks the receptors for platelet growth factor, preventing cancer cell growth and division. Do not use Bosulif if you are pregnant. Use effective birth control during treatment and for at least 1 month after your last dose. Tell your doctor immediately if you become pregnant during treatment. You should not breastfeed while using Bosulif. To make sure Bosulif is safe for you, tell your doctor about any other medications you are currently using, if you have liver, kidney, or heart disease, or if you have a breathing disorder. Grapefruit and grapefruit juice may interact with Bosulif and lead to unwanted side effects. Bosulif can lower blood cells that hep your body fight infections and help your blood to clot. Take care when around sick people, and avoid injury if possible. If you experience any serious side effects, signs of liver problems, signs of low blood cell counts, signs of infection, or signs of an allergic reaction, seek emergency medical attention.
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