Safely Buy Apresoline ( Hydralazine ) from Canada Prescriptions Plus.

Indications

Apresoline is a vasodilator used to treat high blood pressure, pre-eclampsia, and heart failure by helping blood flow more easily through your body.

Hydralazine is a direct arteriole vasodilator that helps maintain blood pressure levels by helping inhibit the release of calcium within your arterial smooth muscles. This action helps improve the release of epinephrine and norepinephrine which helps your blood flow through your body by increasing venous return and cardiac output.

Uses and Dosage

The dose of Apresoline prescribed will vary depending on the person and the severity of their heart condition being treated. Always follow your doctor’s instructions and read packaging carefully.

• Swallow tablet whole
• Most adults initiate treatment with 10mg four times daily
• After 2 to 4 days, most patients increase to 25mg four times daily
• For the second week onwards, most adults take 50mg four times daily
• Adults shouldn’t have more than 300mg daily
• Store at room temperature away from moisture

Side Effects

Apresoline may cause some side effects to develop while it improves your blood pressure. Speak with your doctor for more specific information regarding symptoms you may encounter when taking hydralazine.

Common Apresoline side effects:

• Chest pain, fast heart rate
• Headache
• Nausea, vomiting, diarrhea
• Loss of appetite

Serious Side Effects

Some more serious side effects may occur when taking Apresoline. If you notice any of the following symptoms, stop taking this medication and seek medical attention.

• Chest pain or pressure, pain spreading from your jaw to shoulder
• Fast or pounding heartbeats
• A light-headed feeling, like you might pass out
• Numbness, tingling, or burning in your hands or feet
• Painful or difficult urination
• Little or no urination
• Lupus-like syndrome (joint pain or swelling with fever, swollen glands, muscle aches, chest pain, vomiting, unusual thoughts or behaviour, patchy skin colour)

Allergic Reactions

Do not use Apresoline if you are allergic to Hydralazine. Stop using this medication and contact your doctor if you notice any signs of an allergic reaction.

Apresoline allergy symptoms may include:

• Hives
• Difficulty breathing
• Swelling of face, lips, tongue, or throat

Cautions

Do not use Apresoline if you have coronary artery disease or rheumatic heart disease affecting your mitral valve.

To avoid feeling dizzy, slowly get up from a sitting or lying position.

To ensure the safety of taking Apresoline, tell your doctor if you have ever had any of the following:

• Kidney disease
• Systemic lupus erythematosus
• Angina
• A stroke

Some other medications may interact with hydralazine and cause unwanted effects. Tell your doctor about all the medications you take, including over the counter medicine, vitamins, and herbal products, but especially the following:

• Diazoxide
• An MAO inhibitor (isocarboxazid, linezolid, methylene blue injection, and others)

The effects of hydralazine on an unborn baby are unknown. Consult with your doctor if you are pregnant or plant to become pregnant before taking Apresoline.

Hydralazine can pass into breast milk, but its effects are unknown. Tell your doctor if you are breastfeeding while using Apresoline and monitor your nursing child for any symptoms.

Apresoline is not an approved treatment for anyone under the age of 18.

Form and Strength

This vasodilator is available in tablet form.

Apresoline tablet strengths:

• 10mg
• 25mg
• 50mg

Each Apresoline tablet strength is available in quantities of 100.

FAQ

How should I take Apresoline?

Apresoline should be taken four times each day at similar times with food. Studies have shown that consuming this oral medication with food helped increase the conversion of the drug. Those with hypertension are therefore recommended to take their Apresoline doses with meals.

How does Apresoline work?

The precise mechanism of action for hydralazine is uncertain but researchers believe that this medication works by blocking certain chemicals to help smooth arterial muscles so blood can flow more easily through your body. Part of this is thanks to Apresoline’s increase in the release of epinephrine and norepinephrine.

Resources:

1. https://pubmed.ncbi.nlm.nih.gov/29262006/
2. https://pubmed.ncbi.nlm.nih.gov/6734044/#:~:text=It%20is%20possible%20that%20food,time%20in%20relation%20to%20meals
3. https://www.drugs.com/mtm/apresoline.html
4. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1fd8cf42-66ae-4af5-a5ae-7c9679a0e532