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Home > Drug Category > Cancer Medications > Ofev and Equivalent

Ofev Information

Ofev (Nintedanib Esylate) is used to treat diseases that cause scar tissue formation (fibrosis) deep within the lungs. In these conditions, the scar tissue thickens and becomes stiff with time, making it difficult for you to breathe. You may develop other medical problems if your brain, heart, and other organs do not receive enough oxygen. Ofev is used to treat lung diseases like idiopathic pulmonary fibrosis (IPF) and chronic interstitial lung disease (ILD). The drug is also used to slow lung function decline in people with systemic sclerosis-associated interstitial lung disease (SSc ILD). It is important to note that Ofev does not cure IPF or ILD, but it can slow the effects of these diseases on your lungs. Tyrosine kinase inhibitors like Nintedanib Esylate work by blocking the effects of some substances that cause scarring of the lungs.

Ofev Side Effects

The most common side effects of Ofev may include diarrhea; weight loss; headache; stomach pain; nausea; appetite loss; Call your doctor right away if you have any of the serious side effects such as:
• Bloody stools;
• Severe or ongoing vomiting;
• Shortness of breath;
• Signs of a stroke, such as sudden numbness, slurred speech, problems with vision;
• Signs of liver problems, such as stomach pain, dark urine, appetite loss;
• Wounds that will not heal

Ofev Precautions

Do not use Ofev if you are allergic to Nintedanib Esylate or other ingredients in this medication. Before you start taking this medication, tell your doctor about your medical history, including if you have liver disease; have heart problems; have or have had a blood clot; have a family history of bleeding problems; have had a recent abdominal surgery; have ever had an aneurysm; are pregnant, think you may be pregnant or plan to become pregnant; are breastfeeding, or are planning to breastfeed. Tell your doctor about all the medications you take, including prescription, OTC, herbal supplements, and vitamins. There may be a drug interaction between Ofev and other medications like warfarin; apalutamide; carbamazepine; heparin; phenytoin; phenobarbital; rifampin; St. John’s wort; verapamil;. Do not use Ofev if you are pregnant or planning to become pregnant without informing your doctor. This medication can harm your unborn baby. Avoid getting pregnant while using this drug and for at least 3 months after your last dose. Use a barrier form of birth control to prevent pregnancy. Do not use Ofev while breastfeeding without talking to your doctor. It is not known if Nintedanib Esylate passes into your breastmilk. Do not give this drug to children less than 18 years old. It may harm them. Use your medicine exactly as prescribed by your doctor. Do not stop or change the dose of this medicine without talking to your doctor. Take Ofev by mouth with food. Swallow the capsule whole. The drug has a bitter taste. Do not crush, chew, or open the capsules. If your skin comes in contact with the content inside the capsules, wash your hands immediately. Take your doses at regular intervals. Drink plenty of fluids while using this drug. Keep this medicine out of the sight and reach of children. Store Ofev at room temperature, away from light and moisture.

Do I need a prescription to order Ofev?

Yes, a prescription is required from your physician to order Ofev.