Zyclara Cream (Imiquimod 3.75%)

Zyclara Cream (Imiquimod) 3.75% is prescribed for the treatment of actinic keratosis (AK) of the face or balding scalp in adults with normal immune systems. This medicine is an immune response modifier and works by stimulating your body’s own immune response. Use the cream exactly as prescribed by your doctor. Apply Zyclara cream to the affected area(s) once a day just before bedtime. Maximum daily dose is 500 mg (2 packets of 250 mg each or 2 full actuations of the pump). Zyclara cream should not be applied to areas larger than either the face or balding scalp. The treatment consists of two 2-week treatment cycles, each cycle is separated by two weeks without treatment. Apply a thin layer of Zyclara cream only to the affected area(s) to be treated. Do not use more than two packets or more than two full pump actuations for each application. Rub the cream in all the way to the affected area(s). Avoid the cream in or around your eyes, lips and nostrils. If Zyclara cream accidentally gets in your mouth, your eyes, and nostrils rinse well with water right away. Do not cover the treated area(s). Leave the cream on the affected area(s) for about 8 hours or as instructed by your doctor. Do not bathe or get the treated area(s) wet during the treatment period. After the treatment period, wash the treated area(s) with mild soap and water.

Manufacturer Information

Stop taking Zyclara and call your doctor at once if you have one of these serious side effects:

• Low blood count
• Serious diarrhea

Less serious side effects include redness, scabbing or crusting, flaking or dry skin, swelling, small open sores, drainage; itching, irritation, pain, tiredness, nausea, fever, loss of appetite, dizziness, herpes outbreak, pain, swollen lymph nodes, joint aches, skin irritation, difficulty sleeping. Please call your doctor if you have any further concerns or questions.

Avoid exposure to sunlight, sunlamp or tanning-bed during the treatment with Zyclara. Wear protective clothing and hat if you go outside during daylight. Zyclara may cause severe skin reactions. Zyclara may also cause flu-like symptoms before or during local skin reactions. Do not take Zyclara Cream if you are allergic to imiquimod, or to any other ingredients in the cream. Zyclara cream should not be used in patients under 18 years of age. Before using this cream, inform your doctor if you have other skin cancers or other growths on your body, a weak immune system, hador have any other treatment for actinic keratosis, such as freezing or surgery, are pregnant or breastfeeding. Although, it is not known if Zyclara cream and other medicines can affect each other, you should always tell your health care professional about any medications that you have been taking or are going to take including prescription and non-prescription drugs, vitamins and herbal supplements.

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