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Indications

This is a combination medication that contains 2 active ingredients: pyrethrins and piperonyl butoxide. This medication is used to treat head lice and crab lice infestations.

Pyrethrins belong to the group of medications called insecticides.

Pyrethrins are naturally occurring insecticides extracted from chrysanthemum plants. It works by paralyzing and killing lice.

Piperonyl butoxide increases the time the product is effective by preventing pyrethrin breakdown.

Use and Dosage

Do not use any other product in your hair before using this product. This medication should be applied to dry hair.

Soak your hair as well as the skin of the infested area using at least 25 mL of product. If you have thick or long hair, you should use more than 25 mL. Leave the product on for 10 minutes. Work the product into your hair and skin by using small amounts of water to create a lather. Rinse the product thoroughly. For head lice, comb wet hair with a regular comb to remove tangles. Then, separate a strand of hair no wider than the nit comb and use the nit comb to remove the dead lice and their nits. Wipe off the comb and repeat until all hair has been combed with the nit comb.

Check the hair and remove nits daily for 7 days after treatment. It is recommended that you repeat this process in 7 to 10 days to kill any new lice that may have been hatched since the first treatment. You should not use this product more than 2 times in 24 hours.

Since lice infestations are spread through contact, you should make sure that your family members and sexual partner(s) are examined for lice infestation. If they are infested, they should speak to their doctor or pharmacist immediately about using this product. Also notify your child’s school, daycare, or other people who have been in close contact.

To prevent reinfestation, contaminated items such as bedding, towels, clothing, and hats should be washed in very hot water and dried in the dryer using the hot cycle for at least 20 minutes. If items cannot be washed and dried this way, dry-clean or seal them in a plastic bag for 2 weeks and wash normally. Combs and brushes should be soaked in hot water above 54°C or in undiluted products for 5 to 10 minutes and rinsed with hot water.

If your doctor or pharmacist has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor or pharmacist.

This medication must be used exactly as recommended by your doctor or pharmacist.

Store this medication at room temperature and keep it out of the reach of children. If you have any leftover product, dilute it with water and pour it down the drain. The bottle should be rinsed well and discarded.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using piperonyl butoxide and pyrethrins and call your doctor at once if you have severe stinging, burning, itching, swelling, or irritation where the medication is applied.

Common side effects of piperonyl butoxide and pyrethrins topical may include:

• Mild itching, burning, or stinging
• Mild skin rash
• Numbness or tingly feeling

This is not a complete list of side effects and others may occur.

Cautions

Before using pyrethrin and piperonyl butoxide shampoo, tell your doctor and/or pharmacist:

• If you are allergic to pyrethrin, piperonyl butoxide, chrysanthemums, ragweed, any other medications, or any of the ingredients in pyrethrin and piperonyl butoxide shampoo. Ask your pharmacist for a list of the ingredients.
• What prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take.
• If you have or have ever had skin conditions.
• If you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while using pyrethrin and piperonyl butoxide shampoo, call your doctor.

Forms and Strengths

R&C Shampoo and Conditioner is available in the following forms and strengths:

• R&C Shampoo and Conditioner:
  • 3/0.33 %

FAQ

What happens if I miss a dose?

Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up for the missed dose.

What happens if I overdose?

Seek emergency medical attention.

What should I avoid while using piperonyl butoxide and pyrethrins topical?

Avoid using other medications or skin products on the areas you treat with piperonyl butoxide and pyrethrins topical, unless your doctor tells you to.

Avoid getting this medication in your eyes, nose, mouth, or vagina. If this does happen, rinse with water. Do not use piperonyl butoxide and pyrethrins topical on sunburned, windburned, dry, chapped, irritated, or broken skin.

Avoid close contact with others until the infection has been cured. Avoid sharing hair combs, hair accessories, hats, clothing, bed linens, pillows, and other items of personal use.

Resources:

1. https://www.medbroadcast.com/drug/getdrug/rc-shampoo-with-conditioner
2. https://www.drugs.com/mtm/piperonyl-butoxide-and-pyrethrins-topical.html#side-effects
3. https://medlineplus.gov/druginfo/meds/a601105.html