Safely Buy Trizivir ( Abacavir/Lamivudine/Zidovudine ) from Canada Prescriptions Plus.

Indications

This product contains 3 drugs: abacavir, lamivudine, and zidovudine. Trizivir is used alone or with other HIV medications to help control HIV infection. It helps to decrease the amount of HIV in your body so your immune system can work better. This lowers your chance of getting HIV complications (such as new infections, and cancer) and improves your quality of life.

Abacavir, lamivudine, and zidovudine all belong to a class of drugs known as nucleoside reverse transcriptase inhibitors (NRTIs).

Abacavir/lamivudine/zidovudine is not a cure for HIV infection.

Use and Dosage

Read the Medication Guide and Warning Card provided by your pharmacist before you start taking abacavir/lamivudine/zidovudine each time you get a refill. Carry the Warning Card with you at all times. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with or without food as directed by your doctor, usually twice daily. Take this medication with a full glass of water (8 ounces/240 milliliters) unless your doctor directs you otherwise.

Because this combination product has fixed doses of abacavir, lamivudine, and zidovudine, it should only be used if your doctor has determined that the doses of all 3 medications in this product are right for you.

If you stop taking any medication containing abacavir even for a short time and then restart the drug, you have an increased chance of developing a very serious (possibly fatal) allergic reaction. Refill your medication before you run out. Do not stop treatment unless directed by your doctor. Before restarting any medication containing abacavir, consult your doctor or pharmacist, and be sure you have easy access to medical care.

Continue taking this medication (and other HIV medications) exactly as prescribed by your doctor. Do not skip any doses. Do not increase your dose, take this drug more often than prescribed, or stop taking it (or other HIV medicines) even for a short time unless directed to do so by your doctor. Skipping or changing your dose without approval from your doctor may cause the amount of virus to increase, make the infection more difficult to treat (resistant), or worsen side effects.

For the best effect, take this medication at evenly spaced times. To help you remember, take this medication at the same time every day.

Side Effects

Call your doctor at once if you have symptoms of an allergic reaction from two or more of these specific side effect groups:

• Group 1 – fever
• Group 2 – rash
• Group 3 – nausea, vomiting, diarrhea, stomach pain
• Group 4 – general ill feeling, extreme tiredness, or body aches
• Group 5 – shortness of breath, cough, sore throat

Once you have had an allergic reaction to this medicine, you must never use it again. If you stop taking Trizivir for any reason, talk to your doctor before you start taking it again.

Call your doctor at once if you have:

• Other signs of allergic reaction–skin blisters or peeling, eye redness, swelling in your face or throat, or trouble breathing
• Lactic acidosis–unusual muscle pain, trouble breathing, stomach pain, vomiting, irregular heart rate, dizziness, feeling cold, or feeling very weak or tired
• Low white blood cell counts–fever, mouth sores, skin sores, sore throat, cough, or trouble breathing
• Low red blood cells (anemia)–pale skin, unusual tiredness, feeling light-headed or short of breath, or cold hands and feet
• Liver problems–swelling around your midsection, right-sided upper stomach pain, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes)

Abacavir, lamivudine, and zidovudine affect your immune system, which may cause certain side effects (even weeks or months after you have taken this medicine). Tell your doctor if you have:

• Signs of a new infection–fever, night sweats, swollen glands, cold sores, cough, wheezing, diarrhea, or weight loss
• Trouble speaking or swallowing, problems with balance or eye movement, weakness, or prickly feeling
• Swelling in your neck or throat (enlarged thyroid), menstrual changes, impotence

Common side effects of abacavir, lamivudine, and zidovudine may include:

• Headache
• Weakness or tiredness
• Nausea or vomiting
• Changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist)

This is not a complete list of side effects and others may occur.

Cautions

• Before taking abacavir/lamivudine/zidovudine, tell your doctor or pharmacist if you are allergic to any of these drugs; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
• Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney problems, liver problems (such as hepatitis B or C, cirrhosis), disease of the pancreas (pancreatitis), alcohol use, and low red/white blood cell counts.
• Abacavir may increase your risk of a heart attack. Discuss the risks and benefits of treatment with your doctor and ways to lower your risk of heart disease. Tell your doctor if you have heart problems, if you smoke, or if you have other conditions that increase your risk of heart disease, such as high blood pressure, diabetes, or high cholesterol levels.
• This drug may make you dizzy. Alcohol or marijuana (cannabis) can make you dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Alcohol may also increase the risk of liver problems and pancreatitis. Talk to your doctor if you are using marijuana (cannabis).
• Children may be more sensitive to the side effects of this drug, especially pancreatitis.
• Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
• Tell your doctor if you are pregnant before using this medication. Treatment can lower the risk of passing HIV infection to your baby. Discuss the risks and benefits with your doctor.
• This medication passes into breast milk. Because breast milk can transmit HIV, do not breastfeed.

Forms and Strengths

Trizivir is available in the following forms and strengths:

• Trizivir Film Coated Tablet:
  • 300/150/300mg

FAQ

What happens if I miss a dose?

Take the medicine as soon as you can but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

Get your prescription refilled before you run out of medicine completely. If you miss several doses, you may have a dangerous or even fatal allergic reaction once you start taking this medication again.

What happens if I overdose?

Seek emergency medical attention.

What should I avoid while taking abacavir, lamivudine, and zidovudine?

Taking this medicine will not prevent you from passing HIV to other people. Do not have unprotected sex or share razors or toothbrushes. Talk with your doctor about safe ways to prevent HIV transmission during sex. Sharing drugs or medicine needles is never safe, even for a healthy person.

Resources:

1. https://www.webmd.com/drugs/2/drug-20129/trizivir-oral/details
2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/021205s036lbl.pdf
3. https://www.drugs.com/mtm/abacavir-lamivudine-and-zidovudine.html#side-effects