Lescol (Fluvastatin)

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Fluvastatin 20mg

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Fluvastatin 20mg
Product of United Kingdom
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Fluvastatin 40mg

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Manufactured by: UK Various Generics
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Fluvastatin 40mg
Product of United Kingdom
Manufactured by UK Various Generics
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Fluvastatin 20mg

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Manufactured by: Teva Pharmaceuticals
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Fluvastatin 20mg
Product of Canada
Manufactured by Teva Pharmaceuticals
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Fluvastatin 40mg

Product of Canada
Manufactured by: Teva Pharmaceuticals
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Fluvastatin 40mg
Product of Canada
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Lescol (Fluvastatin) Dosage and Side Effects

LESCOL/LESCOL XL is to be used along with a medically recommended and carefully supervised diet for the long-term treatment of high cholesterol and fatty acids. In addition, depending on your condition, your physician may recommend an appropriate regimen of exercise, weight control and other measures.

Proper Use of this medication

Use only as specifically directed. Do not alter the dosage unless ordered to do so by your physician. Check with your physician before discontinuing medication since this may result in an increase of your fat substances in the blood.

Usual dose, limit to people older than 10 years:

  • If your doctor recommends you take only 1 dose of LESCOL per day, take it in the evening or at bedtime or LESCOL XL at any time of the day. If your doctor recommends taking divided doses (2 times per day), take one in the morning and one in the evening.

  • LESCOL/LESCOL XL can be taken with or without food, but continue to take it the same way (either with OR without food) each time. Swallow LESCOL/LESCOL XL whole with a glass of water.

  • Do not change the dose unless directed by a doctor.

  • Your physician will monitor your clinical condition and your blood tests at regular intervals. It is important to have these check-ups done on schedule. Please keep your appointments accurately.

  • Notify your physician if you are going to have major surgery or have sustained a severe injury.

Overdose:

If you take more LESCOL/LESCOL XL than you should, tell your doctor immediately or go to your nearest hospital.

In case of drug overdose, contact a health care practitioner, hospital emergency department or regional Poison Control Centre immediately, even if there are no symptoms.

Missed dose:

If you forget to take LESCOL/LESCOL XL, take one dose as soon as you remember.

Do not take a double dose to make up for the one that you missed.

Side Effects

As with all medicines, patients treated with LESCOL/LESCOL XL may experience side effects, although not everybody gets them.

Other side effects may occasionally occur which usually do not require stopping treatment. They may come and go during treatment without any particular danger, but you should mention them to your physician, without undue delay, if they become persistent or bothersome. Such adverse experiences include:

  • abdominal pain/indigestion

  • constipation

  • diarrhea

  • nausea

  • headache

  • abnormal blood test values for muscle and liver

  • influenza

  • infections

  • poor memory, confusion and memory loss

  • insomnia and

  • dizziness.

Possible side effects reported with some statins: liver failure (symptoms like nausea, vomiting, loss of appetite, yellow eyes or skin, confusion, euphoria or depression, mental slowing, slurred speech, sleep disturbances, tremors, easy bruising or bleeding), breathing problems including persistent cough and/or shortness of breath or fever, depression, erectile dysfunction, sleep disturbances, including insomnia and nightmares.

If any of these affect you severely, tell your doctor.

LESCOL/LESCOL XL can cause abnormal blood test results. Your doctor will decide when to perform blood tests and will interpret the results.

For any unexpected effects while taking LESCOL/LESCOL XL, contact your doctor or pharmacist.

Warnings and Precautions

Pregnancy:

LESCOL/LESCOL XL should not be used during pregnancy. Cholesterol is essential for the development of a baby. Cholesterol-lowering drugs can harm the baby. If you become pregnant while using LESCOL/LESCOL XL, stop using the medication immediately and contact your doctor.

BEFORE you use LESCOL/LESCOL XL talk to your doctor or pharmacist if you:

  • have thyroid problems

  • regularly drink three or more alcoholic drinks daily

  • are taking any other cholesterol lowering medication such as fibrates (gemfibrozil, fenofibrate, bezafibrate), niacin or ezetimibe

  • are taking any other medications, including prescription, nonprescription and natural health products as drug interactions are possible, in particular corticosteroids, cyclosporine (NEORAL), fibrates (e.g. gemfibrozil [LOPID]), oral anticoagulants (eg. warfarin [COUMADIN]), phenytoin, oral hypoglycemics, non steroidal anti-inflammatory drugs, erythromycin, lipid lowering doses of niacin (nicotinic acid), nefazodone (SERZONE) and colchicines

  • have a personal or family history of muscular disorders

  • had any past muscle problems (pain, tenderness), after using an HMG-CoA reductase inhibitor (“statin”) such as atorvastatin (LIPITOR), fluvastatin (LESCOL/LESCOL XL), lovastatin (MEVACOR), pravastatin (PRAVACHOL), rosuvastatin (CRESTOR) or simvastatin (ZOCOR) or have developed an allergy or intolerance to any of them

  • have unexplained muscle pain, tenderness or weakness, as these might be early signs of potentially severe muscle degradation

  • have kidney disease

  • have liver problems: liver function tests will normally be done before starting LESCOL/LESCOL XL, at dose increase and at various intervals during treatment to check for undesirable effects

  • have severe metabolic, endocrine or electrolyte disorders such as decompensated diabetes and low blood potassium

    Slightly increased blood sugar can occur when you take LESCOL/LESCOL XL Discuss with the doctor your risk of developing diabetes.

  • have undergone surgery or other tissue injury

  • do excessive physical exercise

  • have a serious infection

  • have very low blood pressure (signs may include dizziness, lightheadedness)

  • have congestive heart failure

  • suffer from seizures

  • are older than 70 years your doctor may want to clarify whether you have risk factors for muscular diseases. This may require specific blood tests.

  • In adolescents and children, the safety of LESCOL/LESCOL XL for a prolonged treatment period on their physical, intellectual and sexual maturation has not been established.

Your doctor will monitor your progress with LESCOL/LESCOL XL and may occasionally perform some tests to ensure your health and safety.

Interactions with this medication

Drugs that may interact with LESCOL/LESCOL XL include:

  • corticosteroids

  • cholestyramine

  • gemfibrozil/fenofibrate/bezafibrate/niacin

  • cimetidine/ranitidine/omeprazole

  • digoxin

  • rifampicin

  • warfarin and other coumarin derivatives

  • phenytoin

  • fluconazole

  • oral hypoglycemic agents (e.g. tolbutamide, chlorpropamide, glyburide)

  • non-steroidal anti-inflammatory drugs (NSAIDs)

  • nefazodone

  • alcohol

  • spironolactone

  • amlodipine

  • cyclosporine

Notify your physician about any illness which may develop during your treatment with LESCOL/LESCOL XL and about any new prescription or nonprescription medication you may take. If you require medical help for other reasons, inform the attending physician that you are taking LESCOL/LESCOL XL.

In adolescents and children, no information on specific drug interactions with LESCOL/LESCOL XL is available.

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The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

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