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Indications

Priligy is a urological medication used to treat premature ejaculation (PE) in men aged 18 to 64 years old.

Dapoxetine is a selective serotonin reuptake inhibitor (SSRI) that improves symptoms and the time it takes to ejaculate intravaginally by increasing the availability of certain chemicals in your brain. When taken 1 to 3 hours before sexual contact, Priligy can decrease symptoms of premature ejaculation.

This PE medication is a safe and effective form of treatment that improves sexual performance and experience in men suffering from premature ejaculation. Priligy is generally well-tolerated with the most common adverse effects including nausea, dizziness, and headache.

Uses and Dosage

The dose of Priligy prescribed may vary depending on the individual being treated. Follow all your doctor’s instructions and read packaging labels carefully to ensure the best results.

  • Swallow tablets whole
  • Take with or without food
  • Take with a full glass of water
  • Most men take 30mg 1 to 3 hours before anticipated sexual activity
  • Men should not take more than 60mg a day
  • Do not take your Priligy dose more than once ever 24 hours
  • Consult your doctor after 4 weeks or your first 6 doses to assess your treatment
  • Store at room temperature away from children and pets

Side Effects

Priligy may cause some side effects to develop while improving symptoms of PE. Speak with your doctor for more information regarding any symptoms that you may encounter when taking dapoxetine.

Common Priligy side effects:

  • Dizziness
  • Headache
  • Feeling ill
  • Feeling irritable, anxious, agitated, or restless
  • Numb or tingling sensations
  • Difficulty getting or maintaining an erection
  • Sweating more than usual
  • Diarrhea, constipation, gas
  • Stomach pain, bloating, nausea
  • Insomnia
  • Tiredness
  • Lower sex drive
  • Ringing ears
  • Blurred vision
  • Indigestion
  • Dry mouth

Serious Side Effects

Some more serious adverse reactions may occur when taking dapoxetine. Stop using Priligy and call your doctor right away if you notice any of the following symptoms:

  • Seizures
  • If you feel faint or lightheaded when standing
  • Mood changes
  • Suicidal thoughts or actions
  • Feeling confused, disoriented, or unable to think clearly
  • Slow or irregular heartbeat, increased heart rate
  • Low sex drive, problems reaching orgasm
  • Weakness, tiredness
  • Vision problems, eye pain, dilated pupils
  • Low or high blood pressure

Dapoxetine may cause you to become faint or lower your blood pressure when you stand from a seated or laying position. Drink plenty of water after taking your dose and move slowly when standing up.

Allergic Reactions

Do not take Priligy if you are allergic to dapoxetine or any of the other listed tablet ingredients. If you develop an allergic reaction, stop using this medication and contact your doctor.

Priligy allergy symptoms may include:

  • Hives
  • Difficulty breathing
  • Swelling of face, lips, tongue, or throat

Cautions

Priligy is designed to treat premature ejaculation in men and so should not be taken by women or children.

These Priligy tablets contain lactose; consult with your doctor before taking this medication if you have been told that you are intolerant to certain sugars.

Do not take Priligy if you have ever had any of the following:

  • Heart problems (heart failure, heart rhythm issues)
  • History of fainting
  • Mania (feeling over-excited, irritable, or not being able to think clearly)
  • Severe depression
  • Moderate to severe liver problems

Avoid grapefruit products while taking Priligy because it can interact and cause adverse effects.

Avoid drinking alcohol while using this medication because it can cause an increase in adverse reactions. Alcohol may also increase your risk of injury from fainting or other side effects such as dizziness and tiredness.

Avoid driving or performing any hazardous activities while taking Priligy until you know how the medication will affect you. Dapoxetine may impair your thinking and reactions, causing you to feel dizzy, sleepy, and have trouble concentrating.

Before taking Priligy, tell your doctor if any of the following apply:

  • You have not been diagnosed with PE
  • You have another sexual problem as well as PE like erectile dysfunction
  • You have a history of dizziness from low blood pressure
  • You use recreational drugs
  • You drink alcohol
  • You have ever had mental health issues

To ensure your safety when taking Priligy, tell your doctor if you have any of the following conditions:

  • Epilepsy
  • History of bleeding or blood clotting problems
  • Kidney problems
  • Have or are at risk of glaucoma

To avoid drug interactions, wait 7 days after or 14 days before taking Priligy if you also use any of the following medications:

  • Depression medicines called monoamine oxidase inhibitors
  • Thioridazine for schizophrenia
  • Other medications for depression
  • Lithium
  • Linezolid
  • Tryptophan
  • St. John’s wort
  • Tramadol
  • Migraine medication
  • Certain antifungal medications including ketoconazole and itraconazole
  • Medicines for HIV including ritonavir, saquinavir, and nelfinavir
  • Antibiotics for treating infections including telithromycin
  • The antidepressant nefazodone

Some other drugs may also interact with dapoxetine and cause adverse reactions. To avoid this, tell your doctor about all the medications you take, including any over the counter medicines, but especially any of the following:

  • Medication for mental health problems other than depression
  • Non-steroidal anti-inflammatory drugs (ibuprofen, aspirin, and others)
  • Blood thinners
  • Medicine to treat erectile dysfunction
  • Blood pressure medication
  • Antifungal medicine
  • HIV medication
  • Antibiotics
  • Aprepitant

Form and Strength

This premature ejaculation medication is available in tablet form.

Priligy tablet strengths:

  • 30mg
  • 60mg

The 30mg Priligy tablets are available in quantities of 3, 4, 6, and 24 while the 60mg tablets are available in quantities of 3 and 6.

FAQ

How long does it take for Priligy to work?

Priligy is quickly absorbed into your body and begins taking effect right away. Approximately an hour following your dose, dapoxetine should reach its peak plasma levels in your system and is eliminated within a few hours. This is why the medication is recommended to be taken an hour to 3 hours before you anticipate being sexually active.

Can I drink alcohol after taking Priligy?

You should wait for your dose of Priligy to clear your system before drinking alcohol because taking them at the same time can lead to an increase in adverse effects. Both alcohol and dapoxetine can cause you to be dizzy, sleepy, and disoriented, meaning these effects can worsen when the substances are combined.

Resources:

  1. https://pubmed.ncbi.nlm.nih.gov/20540653/
  2. https://pubmed.ncbi.nlm.nih.gov/21771283/
  3. https://www.medicines.org.uk/emc/files/pil.1269.pdf
  4. https://www.panmerseyapc.nhs.uk/media/2194/dapoxetine.pdf

Additional information

Brand Name:

Priligy

Scientific Name:

Dapoxetine

Other Names:

Duralast, Priligy

Strength(s):

30mg, 60mg

Quantities Available:

3, 4, 6, 24

Formulation:

Tablet