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Indications

Diprolene Lotion is a super-high-potency topical corticosteroid used for the treatment of various skin conditions, such as psoriasis and eczema.

The active ingredient in Diprolene Lotion is augmented betamethasone dipropionate at a concentration of 0.05%. According to the prescribing information, treatment with Diprolene Lotion should be limited to 2 consecutive weeks.

Diprolene Lotion is typically prescribed by a dermatologist and should only be used under the supervision and guidance of a healthcare professional.

Use and Dosage

Read the Patient Information Leaflet if available from your pharmacist before you start using this medication and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Use this medication on the skin only. However, do not use it on the face, groin, or underarms or for diaper rash unless directed to do so by your doctor.

Wash and dry your hands. Before applying the medication, clean and dry the affected area. Apply a thin film of the medication to the affected area and gently rub in as directed by your doctor, usually 1 to 2 times daily. Do not cover, bandage, or wrap the area.

After applying the medication, wash your hands unless you are using this medication to treat the hands. When applying this medication near the eyes, avoid getting it in the eyes as this may worsen or cause glaucoma. Also, avoid getting this medication in the nose or mouth. If you get the medication in these areas, rinse with plenty of water.

Use this medication only for the condition prescribed. Do not use it for longer than 2 weeks in a row or use more than 50 grams of the gel or more than 45 grams of the cream/ointment per week unless directed to do so by your doctor.

Inform your doctor if your condition lasts or gets worse after 2 weeks.

Side Effects

Get emergency medical help if you have signs of an allergic reaction to betamethasone: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using betamethasone and call your doctor at once if you have:

• Severe skin irritation where the medicine was applied
• Signs of skin infection (swelling, redness, warmth, oozing)

Your skin can absorb topical steroid medicine, which may cause steroid side effects throughout the body. Stop using betamethasone and call your doctor if you have:

• Blurred vision, tunnel vision, eye pain, or seeing halos around lights
• Slow wound healing, thinning skin, increased body hair
• Increased thirst or urination, dry mouth, fruity breath odor
• Weight gain, puffiness in your face
• Muscle weakness, tired feeling, depression, anxiety, feeling irritable

Steroids can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using this medicine.

Common betamethasone side effects may include:

• Itching, redness, burning, stinging, or blistering of treated skin
• Skin bruising or shiny appearance
• Folliculitis (redness or crusting around your hair follicles)

This is not a complete list of side effects and others may occur.

Cautions

Before using betamethasone, tell your doctor or pharmacist if you are allergic to it; or to other corticosteroids (such as hydrocortisone, or prednisone); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: poor blood circulation, immune system problems, and certain skin conditions if using the gel (rosacea, perioral dermatitis).

Do not use it if there is an infection or sore present in the area to be treated.

Rarely, using corticosteroid medications for a long time or over large areas of skin can make it more difficult for your body to respond to physical stress. Before having surgery or emergency treatment, or if you get a serious illness/injury, tell your doctor or dentist that you are using this medication or have used this medication within the past few months.

Though it is unlikely, this medication may temporarily slow down a child’s growth if used for a long time. See the doctor regularly so your child’s height can be checked.

During pregnancy, this medication should be used only when needed. Discuss the risks and benefits with your doctor.

It is unknown if this drug passes into breast milk. Similar medications pass into breast milk. Consult your doctor before breastfeeding.

Form and Strengths

Diprolene Lotion is available in the following form and strengths:

• Betamethasone Dipropionate Lotion:
  • 0.05 %

FAQ

What happens if I miss a dose?

Apply the medicine as soon as you can but skip the missed dose if it is almost time for your next dose. Do not apply two doses at one time.

What happens if I overdose?

Seek emergency medical attention if anyone has accidentally swallowed the medication.

Long-term use of high doses can lead to thinning skin, easy bruising, changes in body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.

What should I avoid while using betamethasone?

Do not get betamethasone topical in your eyes. If contact does occur, rinse with water.

Avoid applying betamethasone to the skin of your face, underarm, or groin area without your doctor’s instruction.

Do not use betamethasone to treat any condition that has not been checked by your doctor.

Resources:

1. https://www.webmd.com/drugs/2/drug-7461/diprolene-af-topical/details
2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/019716s032lbl.pdf
3. https://www.drugs.com/betamethasone-topical.html#side-effects