Aubagio (Teriflunomide)
Medication information written by Dr. Larisa Roybal, PharmD
Updated - January 14, 2021
Aubagio (Teriflunomide) Product Information
Aubagio is a medication prescribed for people who suffer from swelling and inflammation in the nervous system. It is classified as a immunomodulator that is used to control multiple sclerosis, and slow down the physical problems caused by the condition.
Also known as teriflunomide, Aubagio is recommended when there is a swelling and inflammation in the nervous system that should be reduced. This medication is also used to reduce relapses in those who have multiple sclerosis. However, Aubagio does not cure multiple sclerosis.
Check Aubagio Cost Online at PricePro Pharmacy
The option that we carry is the brand Aubagio 14 mg option that is manufactured by a company called Genzyme, and 28 tablets cost $1950.00 USD price. The estimated shipping time to USA is 10-18 business days. There is no generic alternative available. Why pay more for your prescription? Save money and time with PricePro Pharmacy.
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Aubagio (Teriflunomide) Medication Information
Uses
Aubagio is a pyrimidine synthesis inhibitor indicated for the treatment of patients with relapsing forms of multiple sclerosis
Dosage
There are oral tablets available in several different strengths:
- 7 mg
- 14 mg
Side Effects
The most common side effects of Aubagio include:
- Alopecia
- ALT increase
- Diarrhea
- Influenza
- Paresthesia
- Nausea
Speak with your doctor or pharmacist for a full list of side effects that applies to you.
Precautions
Elimination of Aubagio can be accelerated by administration of cholestyramine or activated charcoal for 11 days.
Aubagio may decrease WBC. A recent CBC should be available before starting Aubagio. Monitor for signs and symptoms of infection. Consider suspending treatment with Aubagio and using accelerated elimination procedure in case of serious infection. Do not start Aubagio in patients with active infections.
Peripheral neuropathy: If patient develops symptoms consistent with peripheral neuropathy, evaluate patient and consider discontinuing Aubagio and using accelerated elimination procedure.
Acute renal failure/hyperkalemia: Monitor renal function and potassium in patients with symptoms of renal failure or hyperkalemia.
Severe skin reaction: Stop Aubagio and use accelerated elimination procedure.
Blood pressure: Measure at treatment initiation. Monitor and manage appropriately during treatment
Interactions
Some of the common drug interactions with Aubagio:
- Ethinylestradiol
- Levonorgestrel
- Duloxetine
- Alosetron
- Theophylline
- Repaglinide
- Pioglitazone
- Paclitaxel
- Warfarin
For a more complete list speak with your doctor or pharmacist
Storage
Store at controlled room temperature (77ºF).
Pharmacist Tips
- Take Aubagio once daily as prescribed.
- Do not to discontinue Aubagio without first discussing with the prescribing physician.
- Aubagio may increase liver enzymes and that their liver enzymes will be checked before starting Aubagio and for at least 6 months while they are taking Aubagio.
- Contact your physician if they have any unexplained nausea, vomiting, abdominal pain, fatigue, anorexia, or jaundice and/or dark urine.
Aubagio FAQs
Can I take this with food?
Aubagio can be taken with or without food.
Can I take this if I am pregnant?
There are no adequate and well-controlled studies evaluating Aubagio in pregnant women. However, based on animal studies, teriflunomide may increase the risk of teratogenic effects or fetal death when administered to a pregnant woman. Aubagio is contraindicated in pregnant women or women of childbearing potential who are not using reliable contraception. Pregnancy must be avoided during Aubagio treatment or prior to the completion of an accelerated elimination procedure after Aubagio treatment.
Can I take this while breastfeeding?
Teriflunomide was detected in rat milk following a single oral dose of teriflunomide. It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in nursing infants from Aubagio a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
Who should not take Aubagio?
If you have severe liver problems, are pregnant or are of childbearing age and not using effective birth control, or take a medicine called leflunomide.
What is the active ingredient in Aubagio?
Teriflunomide
What is Aubagio used for?
Aubagio is used for the treatment of multiple sclerosis.
Related Drugs
Reference:
Aubagio {package insert}. Cambridge, MA: Genzyme Corporation; 2012.
https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/202992s000lbl.pdf
Author: Dr. Larisa Roybal, PharmD
Dr. Roybal is a board-certified pharmacotherapy specialist who has practiced in both ambulatory and acute care settings. Her pharmacy interests include oncology and general inpatient pharmacy.
The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.
