Cyclogest (Progesterone Vaginal Tablet)

Cyclogest (Progesterone Vaginal Tablet) is a prescription medication used in the treatment of premenstrual syndrome (PMS), including premenstrual tension and depression, postnatal depression, and women who need extra progesterone while undergoing treatment in an assisted reproductive technology (ART) program, such as IVF (in vitro fertilization). Cyclogest contains progesterone, which is a naturally occurring female sex hormone produced in the body that is necessary for normal functioning of the reproductive system. Cyclogest works by adjusting the hormonal balance within the body, in order to treat certain symptoms typically caused by a hormonal imbalance. For use during ART, it helps to establish and maintain pregnancy. It also prevents the increase in thickness of the endometrium (lining of the uterus) caused by estrogen. Take this medication as directed by your doctor. Do not use it in larger or smaller amounts, or for longer than recommended. This medication is not for oral use. Cyclogest should be inserted vaginally or rectally. For treatment of post natal depression, the dosage is typically 200mg daily to 400mg twice a day, by vaginal or rectal insertion. For premenstrual syndrome, commence treatment on day 14 of menstrual cycle and continue treatment until onset of menstruation.

Manufacturer Information

Common side effects of Cyclogest may include swelling in the abdomen, abdominal pain, constipation, drowsiness, hot flashes, and breast pain. Contact your doctor if you experience any more severe side effects such as:

• Increase in urination;
• Itching at the application site, feeling cold or body temperature change;
• Night sweats, skin rash or itching;
• Pelvic pain, ovarian enlargement, vaginal bleeding;
• Rapid weight gain

This is not a complete list of side effects, and others may occur. If any of these side effects worsen or persist, or if you experience any serious side effects not listed above, contact your doctor.

Do not use Cyclogest if you are allergic to progesterone or any of the other ingredients of this medication. As well, do not use this medication if you have ever had unusual vaginal bleeding that is not been evaluated by a doctor, a tumor that is hormone sensitive, porphyria disorders (a group of inherited or acquired disorders of certain enzymes), blood clots in the legs, lungs, eyes, or elsewhere in the body, or severe liver problems. To make sure Cyclogest is safe for you, tell your doctor if you have ever had liver problems such as jaundice (yellowing of the skin and whites of the eyes closed parentheses, epilepsy, migraines, asthma, cardiac or renal dysfunction , or diabetes.

Cyclogest can be used during the first trimester of pregnancy for women who need extra progesterone while undergoing treatment in an assisted reproductive technology program. The risks of birth defects has not been fully established. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. This medication can pass into breast milk, and may harm a nursing baby. Do not use this medication while breastfeeding. Cyclogest may interact with several medications, especially carbamazepine, rifampicin, or phenytoin. Using other vaginal products at the same time as Cyclogest is used vaginally is not recommended, as it is not known if it affects the treatment. Do not stop taking this medication suddenly without medical advice. Abrupt discontinuation of progesterone may cause increased anxiety, moodiness, and increased sensibility to seizures. The efficacy of this medication has not yet been fully established in children. Do not give this medication to a child without medical advice.

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