Mysoline (Primidone)

MYSOLINE comes as a tablet to take by mouth. It’s typically taken three to four times daily.

Try to take this medicine around the same time each day. You can take it with or without food.

Follow the instructions on your prescription label carefully. Don’t take more or less MYSOLINE than is prescribed.

Your doctor will likely start you on a low dose of the drug and gradually increase it.

MYSOLINE Overdose

Symptoms of an overdose may include:

• Confusion
• Trouble breathing
• Uncontrolled eye movements

If you suspect an overdose, contact a poison control center or emergency room immediately.

Missed Dose of MYSOLINE

If you miss a dose of MYSOLINE, take it as soon as you remember.

However, if it’s almost time for you next dose, skip the missed dose and continue on your regular dosing schedule.

Don’t double up on doses to make up for a missed one.

Common Side Effects of MYSOLINE

Tell your doctor if any of the following side effects are severe or don’t go away:

• Dizziness
• Tiredness
• Difficulty coordinating movements
• Nausea or vomiting
• Loss of appetite

Serious Side Effects of MYSOLINE

Tell your doctor right away if you experience any of the symptoms listed in the MYSOLINE Warnings section above, or any of the following serious side effects:

• New or worsening seizures
• Double vision or unusual eye movements
• Decrease in sexual ability
• Severe tiredness or weakness
• Signs of an allergic reaction, which may include rash, hives, itching, difficulty breathing, or swelling of the mouth, face, lips, or tongue

Some people may have suicidal thoughts or changes in mental health while taking anticonvulsants such as MYSOLINE.

Tell your doctor right away if you experience any of the following symptoms:

• Panic attack
• Anxiety
• Agitation or restlessness
• New or worsening irritability
• Depression
• Acting on dangerous impulses
• Difficulty sleeping
• Aggressive, angry, or violent behaviors
• Abnormally excited mood
• Suicidal thoughts or actions
• Preoccupation with death
• Withdrawing from family and friends
• Other unusual changes in mood or behavior

Before taking MYSOLINE, tell your doctor if you have or have ever had:

• Porphyria (a blood disease)
• Allergies to any medications
• A history of mental health disorders or substance abuse
• Liver disease
• Lung or breathing problems

Also, be sure to tell your doctor if you’re taking sodium oxybate (Xyrem) or the recreational drug GHB before starting MYSOLINE.

Tell your doctor that you take MYSOLINE before any type of surgery, including dental procedures.

It might take several weeks before you feel the full benefits of MYSOLINE.

Don’t stop taking the medicine without first talking to your doctor. Your seizures may become worse and you may experience unpleasant withdrawal symptoms if you stop taking MYSOLINE suddenly.

Be sure to keep all appointments with your doctor and laboratory while taking this medicine.

Pregnancy and MYSOLINE

MYSOLINE may harm an unborn baby. Don’t take this medicine if you’re pregnant or plan to become pregnant.

You should also know that hormonal birth control pills may not work as well if you’re taking MYSOLINE. Talk to your doctor about other birth control options.

The drug is found in breast milk and may hurt a breastfeeding baby. Don’t breastfeed while taking MYSOLINE.

Tell your doctor about all prescription, non-prescription, illegal, recreational, herbal, nutritional, or dietary drugs you’re taking, especially those listed in the MYSOLINE Warnings section above, and any of the following:

• Anticoagulants (blood thinners) such as warfarin (Coumadin, Jantoven)
• Antidepressants
• Disulfiram (Antabuse)
• Doxycycline (Vibramycin)
• Griseofulvin (Grifulvin)
• Medications for anxiety, mental illness, or pain
• Other medications for seizures such as oxcarbazepine (Trileptal), phenobarbital, phenytoin (Dilantin), and valproic acid (Depakene, Depakote)
• Oral contraceptives (birth control pills)
• Oral steroids such as dexamethasone (Decadron, Dexone) and prednisone (Deltasone)
• Sedatives
• Sleeping pills
• Tranquilizers

MYSOLINE and Other Interactions

MYSOLINE may make you drowsy.

Don’t drive a car or operate machinery until you know how this medicine affects you.

MYSOLINE and Alcohol

Drinking alcohol may worsen certain side effects of MYSOLINE.

Talk to your doctor about this potential interaction.