Daypro (Oxaprozin)

Indications

Daypro is a prescription medication indicated to reduce pain, stiffness, and inflammation associated with rheumatoid arthritis and osteoarthritis. It contains the active ingredient oxaprozin Oxaprozin belongs to a class of medications called nonsteroidal anti-inflammatory drugs (NSAIDs). Daypro works by reducing inflammation in the body and blocking the production of certain hormones that cause pain and swelling.

Oxaprozin is available as caplets of 600 mg for oral administration and the recommended dosage and duration of treatment may vary based on individual circumstances and medical history.

Uses and Dosage

Daypro comes in tablet form and is usually taken orally with a full glass of water, unless otherwise directed by your healthcare provider. It is typically taken with food or milk to prevent stomach upset. If you miss a dose, take it as soon as possible and continue with your regular dosing schedule. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

The recommended adult dosage of Daypro tablet ranges from 600 mg daily to 1,800 mg daily, taken in 1 or 2 doses with food or milk. If taking 1,800 mg daily, it should be divided into a 1,200 mg dose in the morning and a 600 mg dose in the evening. Do not dispose of medications in wastewater or household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or expired.

Side effect

Common Side Effects of Daypro (Oxaprozin):

• Stomach upset
• Diarrhea
• Constipation
• Vomiting
• Flatulence
• Dry mouth

Serious Side Effects of Daypro (Oxaprozin):

• Bloody stools
• Chills, fever, or flu-like symptoms
• Muscle aches
• Shortness of breath
• Vision changes
• Wheezing
• Confusion
• Edema (swelling) of the lower extremities
• Fatigue
• Headaches
• Lightheadedness
• Loss of hearing
• Mood changes/depression
• Persistent vomiting, nausea, or diarrhea
• Problems or difficulty urinating

Form and strength

Daypro (Oxaprozin) is available in the following forms and strength

Oxaprozin: Tablet

• 600 mg

Caution

• Increased risk of cardiovascular events such as heart attack or stroke
• Gastrointestinal bleeding or ulcers, which can be severe or even fatal, and may occur without warning.
• Hepatotoxicity (liver damage), which can be severe or even fatal, and may occur without warning.
• Hypersensitivity reactions, such as anaphylaxis, skin rash, and other allergic reactions
• Renal toxicity (kidney damage), especially in those with pre-existing kidney disease or dehydration.
• Increased risk of bleeding, especially when taken with other medications that affect blood clotting and increased risk of serious skin reactions.
• Patients should be cautious when driving or operating heavy machinery while taking Daypro, as it can cause dizziness or drowsiness.
• The use of Daypro may increase the risk of cardiovascular thrombotic events including heart attack and stroke, particularly in patients with preexisting cardiovascular disease.
• Daypro should be used with caution in patients with a history of gastrointestinal disease or those who are at higher risk for gastrointestinal bleeding, such as the elderly and those taking blood thinners.
• Daypro may cause or worsen hypertension (high blood pressure) and should be used with caution in patients with this condition.
• Some patients may experience kidney dysfunction while taking Daypro, and those with preexisting kidney problems are at higher risk.
• Patients should be cautious when driving or operating heavy machinery while taking Daypro, as it can cause dizziness or drowsiness.

Frequently Asked Questions (FAQ)

Can I take Daypro/Naproxen sodium with other medications?

Talk to your healthcare provider before taking Daypro/Naproxen sodium with other medications, as it can interact with certain drugs such as blood thinners, lithium, and corticosteroids. Make sure to inform your healthcare provider of all medications you are currently taking or have taken in the past.

Is Daypro/Naproxen sodium addictive?

Daypro/Naproxen sodium is not considered addictive. However, take this medication only as directed by your healthcare provider and to not exceed the recommended dose or duration of treatment.

Is it safe to take oxaprozin (Daypro) if I'm pregnant?

It's not clear whether or not oxaprozin (Daypro) is safe to take during early pregnancy. But the FDA (Food and Drug Administration) recommends that you avoid taking oxaprozin (Daypro) during the second half of pregnancy (week 20 of pregnancy or later).

Resources

• https://www.medbroadcast.com/drug/getdrug/daypro
• https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/18841s022lbl.pdf
• https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=ea1de47e-3101-4414-817c-0a098af8988c
• https://www.drugs.com/mtm/daypro.html
• https://www.webmd.com/drugs/2/drug-6746/daypro-oral/details
• https://www.mayoclinic.org/drugs-supplements/oxaprozin-oral-route/side-effects/drg-20069737?p=1
• https://www.goodrx.com/oxaprozin/what-is