Eulexin (Flutamide)

Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

EULEXIN is usually taken every 8 hours. Follow your doctor's instructions.

Call your doctor if you have severe or ongoing diarrhea. Your doctor may recommend an anti-diarrhea medicine.

Drink plenty of liquids while you are taking EULEXIN. Your doctor may recommend a special diet to help prevent diarrhea.

While using EULEXIN, you may need frequent blood tests.

EULEXIN is given as part of a combination prostate cancer treatment with another medicine called a luteinizing (LOO-tee-in-ize-ing) hormone-releasing hormone, or LHRH. These medicines prevent the testicles from producing testosterone.

You should not stop using EULEXIN suddenly. Stopping suddenly may make your condition worse.

Store at room temperature away from moisture, heat, and light.

Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.

Seek emergency medical attention or call the Poison Help line.

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

Call your doctor for instructions if you miss an appointment for your LHRH injection.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

EULEXIN can cause serious liver problems. Call your doctor at once if you have:

• nausea, upper stomach pain, loss of appetite;
• itching, tired feeling, flu-like symptoms;
• dark urine, clay-colored stools; or
• jaundice (yellowing of the skin or eyes).

Common side effects may include:

• breast swelling or tenderness;
• hot flashes;
• vomiting, diarrhea; or
• impotence, loss of interest in sex.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

EULEXIN can cause serious liver problems. Call your doctor at once if you have upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes).

You will need frequent blood tests to check your liver function while you are taking EULEXIN .

You should not use this medicine if you are allergic to EULEXIN.

EULEXIN should never be taken by a woman or a child.

Although EULEXIN is not for use by women, this medicine can cause birth defects if a woman is exposed to it during pregnancy.

To make sure EULEXIN is safe for you, tell your doctor if you have:

• liver disease;
• a genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency
• hemoglobin M disease;
• if you smoke; or
• if you also take a blood thinner (warfarin, Coumadin, Jantoven).

To help prevent diarrhea, avoid dairy products such as milk, cheese, and yogurt. Do not use laxatives while taking EULEXIN.

This medicine can pass into body fluids (urine, feces, vomit). Caregivers should wear rubber gloves while cleaning up a patient's body fluids, handling contaminated trash or laundry or changing diapers. Wash hands before and after removing gloves. Wash soiled clothing and linens separately from other laundry.

Other drugs may interact with EULEXIN, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.