Safely Buy Wellbutrin SR ( Bupropion SR ) from Canada Prescriptions Plus.

Indications

Wellbutrin SR is an antidepressant medication used to treat major depressive disorder (MDD) and seasonal affective disorder (SAD).

Bupropion is an aminoketone antidepressant drug that inhibits the neuronal reuptake of norepinephrine and dopamine and affects the mechanisms of these chemicals in your brain. These actions help increase the availability of noradrenaline and dopamine to balance your brain chemicals. Thanks to this, Wellbutrin SR can reduce your symptoms of MDD and SAD.

Dosage and Administration

The dose of Wellbutrin SR that is prescribed will vary depending on the individual and depressive disorder being treated. Follow all your healthcare provider’s directions of use and read packaging instructions for the best therapeutic response. Do not change your dose or suddenly stop taking Wellbutrin.

• Swallow tablet whole, do not crush or chew
• Take doses at the same time each day with or without food
• Do not take any other medications during treatment with Wellbutrin unless told to do so by your healthcare provider
• Wellbutrin SR may take several weeks to provide an improvement in your MDD symptoms
• Continue taking Wellbutrin SR as prescribed even if you feel well
• Store at room temperature away from children and pets

To treat MDD and SAD:

• Adults should take a low dose and gradually increase to reduce the risk of seizures
• The first three days of treatment, adults should take 150mg once daily in the morning
• Following these 3 days, doses can increase to 150mg taken twice daily
• Doses should be taken at least 8 hours apart
• Adults should not take more than 400mg daily taken as 200mg twice a day
• Patients with severe liver impairment should take no more than 100mg daily or 150mg taken every other day

Side Effects

Wellbutrin SR may cause some side effects to occur while altering the chemicals in your brain. Speak with your healthcare provider for more information about any symptoms that you may experience.

Common Wellbutrin SR side effects:

• Dry mouth, sore throat, stuffy nose
• Ringing ears
• Blurred vision
• Nausea, vomiting, stomach pain
• Decreased appetite, constipation
• Insomnia
• Tremors, sweating, anxiety
• Fast heart rate
• Confusion, agitation, hostile feelings
• Rash
• Weight loss
• Increased urination
• Headache, dizziness
• Muscle or joint pain

Serious Side Effects

Some more serious adverse effects may develop when taking Wellbutrin SR. Contact your healthcare provider right away if you notice any of the following symptoms:

• Seizures
• Confusion, unusual changes in your mood or behaviour
• Blurred or tunnel vision, eye pain or swelling
• Seeing halos around lights
• Fast or irregular heart rate
• Manic episode (racing thoughts, increased energy, reckless behaviour, feeling extremely happy or irritable, speaking more than normal, severe sleep problems)

Tell your healthcare provider about any new or worsening symptoms that you have, including changes in your mood or behaviour, anxiety, depression, panic attacks, difficulty sleeping, or if you feel impulsive, irritable, hostile, restless, hyperactive, more depressed, or have suicidal thoughts.

Allergic Reactions

Do not use Wellbutrin SR if you are allergic to bupropion or any of the other tablet ingredients. Stop using this medication and contact your healthcare provider immediately if you notice any of the following signs of an allergic reaction:

• Hives, itching
• Fever
• Swollen glands
• Difficulty breathing
• Swelling in your face or throat
• Sore throat
• Burning eyes
• Skin pain
• Red or purple skin rash
• Blistering or peeling skin

Cautions

• Do not take Wellbutrin SR if you have any of the following conditions:
  • Seizure disorder
  • Eating disorder like anorexia or bulimia
  • If you have recently suddenly stopped using alcohol, seizure medicine, or a sedative
• Do not use a monoamine oxidase inhibitor (MAOI) for 14 days before or after taking Wellbutrin SR because the medications could cause a dangerous interaction. MAOIs include isocarboxazid, linezolid, phenelzine, and rasagiline.
• Wellbutrin SR may cause you to have seizures, especially if you have a history of certain medical conditions or take specific drugs. Start treatment at a low dose and gradually increase to reduce your risk.
• To ensure your safety when taking Wellbutrin, tell your healthcare provider if you have ever had any of the following:
  • Head injury, seizures
  • Brain or spinal cord tumour
  • Narrow-angle glaucoma
  • Heart disease, high blood pressure, or a heart attack
  • Diabetes
  • Kidney or liver disease
  • Any mental illness including bipolar disorder
  • If you drink large amounts of alcohol
• Some adolescents and young adults who take antidepressants including Wellbutrin may develop new or worse suicidal thoughts or actions when first starting treatment. Report any changes in your mood or symptoms to your healthcare provider.
• Avoid drinking alcohol, especially in large quantities, while taking Wellbutrin SR because it can increase your risk of developing adverse reactions. Speak with your healthcare provider before you stop drinking if you normally drink regularly because doing so could increase your chance of developing a seizure.
• Wellbutrin SR could cause you to become dizzy, drowsy, or have changes in your vision. Avoid driving or performing hazardous tasks until you know how this medication will affect you.
• If you are pregnant, speak with your healthcare provider about risks and benefits of treatment with Wellbutrin SR. It is unclear how this medication may affect your unborn baby, but having a relapse in your depression may be dangerous. Do not stop taking Wellbutrin without first speaking to your healthcare provider.
• Ask your healthcare provider before breastfeeding while taking Wellbutrin SR because it may or may not affect your nursing child.
• Some drugs may interact with Wellbutrin SR and cause adverse reactions. Tell your healthcare provider about all the medications you take, including over the counter medicines, but especially any of the following:
  • CYP2B6 inducers (ritonavir, lopinavir, efavirenz, carbamazepine, phenobarbital, and phenytoin)
  • Other antidepressant medications (venlafaxine, nortriptyline, imipramine, desipramine, paroxetine, fluoxetine, or sertraline)
  • Certain antipsychotics (haloperidol, risperidone, thioridazine)
  • Beta-blockers like metoprolol
  • Certain antiarrhythmic drugs (propafenone, flecainide, and others)
  • Digoxin
  • Any drug that increases your risk of seizures
  • MAOIs (isocarboxazid, linezolid, phenelzine, and others)
• Wellbutrin SR is not an approved method of treatment for anyone under the age of 18.

Form and Strength

This antidepressant medicine is available in the form of sustained-release tablets.

• Wellbutrin SR tablet strengths:
  • 100mg
  • 150mg

The 100mg Wellbutrin SR tablets are available in quantities of 60 and 120 while the 150mg tablets are available in quantities of 100 and 200.

FAQ

How many hours apart should you take Wellbutrin SR?

It is recommended that you take your daily doses of Wellbutrin SR at least 8 hours apart. Take your doses at the same times each day for the best results. When you first start treatment, your healthcare provider may prescribe you to take Wellbutrin once a day for the first 3 days. In this instance, you should take your doses in the morning each day.

Can you take Wellbutrin SR at night instead of in the morning?

Wellbutrin SR maintenance doses are usually taken twice each day at least 8 hours apart and not exceeding 200mg at once. When starting treatment, however, it is often recommended that you take a low dose every morning for 3 days.

This is because Wellbutrin may affect your ability to fall asleep. If you experience insomnia, try to take your last dose of the day sooner before going to bed.

Resources:

1. https://www.drugs.com/mtm/wellbutrin-sr.html
2. https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=cbc8c074-f080-4489-a5ae-207b5fadeba3&type=display
3. https://dailymed.nlm.nih.gov/dailymed/medguide.cfm?setid=cbc8c074-f080-4489-a5ae-207b5fadeba3