Celexa (Citalopram)

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Celexa 20mg

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Manufactured by: Lundbeck
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Celexa is also marketed as Cipramil
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Citalopram 10mg

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Citalopram 10mg
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Citalopram 20mg

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Citalopram 40mg

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Citalopram 10mg

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Manufactured by: Jamp Pharma Corp.
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Citalopram 10mg
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Citalopram 20mg

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Citalopram 40mg

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Manufactured by: Apotex Inc
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Citalopram 40mg
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Manufactured by Apotex Inc
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Celexa 20mg

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Manufactured by: Lundbeck
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Celexa 20mg
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Celexa 40mg

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Celexa (Citalopram) Medication Information

Uses

Celexa (citalopram) is indicated for the treatment of depression.

Dosage

There are oral tablets available in several different strengths:

  • 10 mg
  • 20 mg
  • 40 mg

Side Effects

The most common side effects of Celexa include:

  • Asthenia
  • Nausea
  • Dry mouth
  • Vomiting
  • Dizziness
  • Insomnia
  • Somnolence
  • Agitation

Speak with your doctor or pharmacist for a full list of side effects that applies to you.

Precautions

SSRIs and SNRIs, including Celexa, may increase the risk of bleeding events. Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs, warfarin, and other anticoagulants may add to the risk. Case reports and epidemiological studies (case-control and cohort design) have demonstrated an association between use of drugs that interfere with serotonin reuptake and the occurrence of gastrointestinal bleeding. Bleeding events related to SSRIs and SNRIs use have ranged from ecchymoses, hematomas, epistaxis, and petechiae to life-threatening hemorrhages.

Hyponatremia may occur as a result of treatment with SSRIs and SNRIs, including Celexa. In many cases, this hyponatremia appears to be the result of the syndrome of inappropriate antidiuretic hormone secretion (SIADH), and was reversible when Celexa was discontinued.

Activation of mania/hypomania has also been reported in a small proportion of patients with major affective disorders treated with other marketed antidepressants. As with all antidepressants, Celexa should be used cautiously in patients with a history of mania.

During marketing of Celexa and other SSRIs and SNRIs (serotonin and norepinephrine reuptake inhibitors), there have been spontaneous reports of adverse events occurring upon discontinuation of these drugs, particularly when abrupt, including the following: dysphoric mood, irritability, agitation, dizziness, sensory disturbances (e.g., paresthesias such as electric shock sensations), anxiety, confusion, headache, lethargy, emotional lability, insomnia, and hypomania. While these events are generally self-limiting, there have been reports of serious discontinuation symptoms. Patients should be monitored for these symptoms when discontinuing treatment with Celexa. A gradual reduction in the dose rather than abrupt cessation is recommended whenever possible. If intolerable symptoms occur following a decrease in the dose or upon discontinuation of treatment, then resuming the previously prescribed dose may be considered. Subsequently, the physician may continue decreasing the dose but at a more gradual rate.

Interactions

Some of the common drug interactions with Celexa:

  • SNRIs
  • SSRIs
  • Triptans
  • Alcohol
  • MAOIs
  • NSAIDs
  • Cimetidine
  • Digoxin
  • Lithium
  • Warfarin
  • Ketoconazole
  • Carbamazepine 

Speak with your doctor or pharmacist for more information. 

Storage

Store at controlled room temperature (77ºF). 

Pharmacist Tips

  • Celexa and other antidepressant medicines may increase suicidal thoughts or actions in some children, teenagers, or young adults within the first few months of treatment or when the dose is changed.
  • Keep all follow-up visits with your healthcare provider and call between visits if you are worried about symptoms.
  • Do not stop Celexa without first talking to your healthcare provider. Stopping Celexa too quickly may cause serious symptoms.

Citalopram FAQs

Can I take this with food?

Celexa may be taken with or without food.

 

Can I take this if I am pregnant?

There are no adequate and well-controlled studies in pregnant women; therefore, citalopram should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

 

Can I take this while breastfeeding?

Citalopram is excreted in human breast milk. There have been two reports of infants experiencing excessive somnolence, decreased feeding, and weight loss in association with breastfeeding from a citalopram-treated mother. The decision whether to continue or discontinue either nursing or Celexa therapy should take into account the risks of citalopram exposure for the infant and the benefits of Celexa treatment for the mother.

 

What is Celexa?

Celexa is a prescription medicine used to treat depression.

 

What should I avoid while taking Celexa?

Celexa can cause sleepiness or may affect your ability to make decisions, think clearly, or react quickly. You should not drive, operate heavy machinery, or do other dangerous activities until you know how Celexa affects you. Do not drink alcohol while using Celexa.

 

How should I take Celexa?

Take Celexa exactly as prescribed. Your healthcare provider may need to change the dose of Celexa until it is the right dose for you. If you miss a dose of Celexa, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses of Celexa at the same time.

 

Related Drugs

Reference:

Celexa {package insert}. St. Louis, MO: Forest Pharmaceuticals, Inc.; 2011.

https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/020822s042,021046s019lbl.pdf

PharmD Medical Writer

Author: Dr. Larisa Roybal, PharmD

Dr. Roybal is a board-certified pharmacotherapy specialist who has practiced in both ambulatory and acute care settings. Her pharmacy interests include oncology and general inpatient pharmacy.

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The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

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