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Indications

Edronax is a medication used for the treatment of depression, including severe forms of depression. It contains Reboxetine, which belongs to a group of drugs called selective noradrenaline reuptake inhibitors.

Edronax works by increasing the levels of noradrenaline in the brain, which is a neurotransmitter that is involved in regulating mood.

Edronax is intended for use in the intensive treatment of depression as well as in the maintenance treatment of patients who respond well to the drug. It requires a prescription from a doctor and should only be used under medical supervision.

Use and Dosage

It comes as a tablet to take by mouth, with or without food.

The recommended therapeutic dose for adults is 4 mg twice a day (8 mg/day) administered orally. This is the recommended starting dose which may be adjusted as required.

A lower starting dose may be recommended for elderly patients and patients with renal or hepatic impairment.

There is no recommended dose for children or adolescents under the age of 18, as there is no available data on its use in this age group. Follow the instructions of your healthcare provider regarding the use and dosage of any medication.

Side Effects

Some of the side effects of Edronax (reboxetine) which have been reported in various studies and clinical trials include headache, loss of appetite, anxiety, agitation, paraesthesia (pins and needles), urinary tract symptoms, and gastrointestinal disturbances.

The most common side effects are nausea, vomiting, constipation, and dry mouth. Additionally, Edronax has been associated with an increased risk of suicidal ideation and behaviour in some patients.

Speak to your healthcare provider if you experience any concerning side effects while taking this medication.

Cautions

Reboxetine, which is also known as Edronax, has several cautions associated with its use. Here are some of the cautions that should be considered when using reboxetine:

• Patients with an increased risk of mydriasis (excessive dilation of the pupils) should not be given reboxetine or should be given it with caution. (source 1)
• Reboxetine can cause urinary hesitancy, so caution should be taken in patients with urinary issues. (source 2)
• Reboxetine has not been approved by the FDA for the treatment of depression and should be used with caution. (source 3)
• Reboxetine should be used with caution in patients with certain conditions, such as cardiovascular disease and bipolar disorder. (sources 4 and 9)
• Reboxetine may interact with other medications, such as fluvoxamine and tricyclics, so caution should be taken when using it concomitantly with other drugs. (sources 5 and 6)

Note that this is not a comprehensive list, and caution should always be taken when using any medication. It is important to discuss the risks and benefits of any medication with a healthcare provider and follow their instructions carefully.

Form and Strengths

Edronax is available in the following form and strengths:

• Edronax Tablet:
  • 4 mg

FAQ

Is Edronax safe during pregnancy?

The use of Edronax during pregnancy is not recommended, as it may be harmful to the developing fetus.

How is Edronax taken?

Edronax is taken orally in tablet form, usually once or twice a day. It should be taken with food to reduce the risk of gastrointestinal side effects.

Can Edronax be taken with other medications?

Edronax may interact with other medications, so it is important to inform your doctor of all medications you are taking before starting treatment with Edronax.

How long does it take for Edronax to start working?

It may take several weeks for Edronax to reach its full effect and improve symptoms of depression.

Resources:

1. https://pubmed.ncbi.nlm.nih.gov/10672775/
2. https://www.medindia.net/doctors/drug_information/reboxetine.htm#General
3. https://go.drugbank.com/drugs/DB00234