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What Is Myrbetriq (Mirabegron)?

Myrbetriq medication belongs to a class of medicines known as Beta-3 adrenergic agonists. It is used to treat overactive bladder (OAB) in adults with symptoms like urgency, frequency, and leakage. In addition, it is used to treat neurogenic detrusor overactivity (NDO) in children three years old and older weighing 35 kg and more. Myrbetriq’s generic alternative is Mirabegron.

The detrusor muscle in the bladder usually relaxes to allow the bladder to fill with urine. When urinating, the detrusor muscle contracts to allow urine to be released.

With OAB, the detrusor muscle contracts most of the time, squeezing the bladder and decreasing the amount of urine it can hold. Therefore, even though your bladder is not yet full, it forces you to urinate frequently and urgently. Furthermore, it can also lead to accidental urination (incontinence), where you cannot make it to the bathroom in time.

When this oral medication is administered correctly and absorbed into the bloodstream, it works by attaching to a beta-3 receptor on the detrusor muscles.

This attachment causes the muscles to relax, allowing the bladder to store more urine. This relieves the symptoms of OAB by helping you reduce the number of times you urinate and prevent incontinence.

How to Use Myrbetriq (Mirabegron)

The dosage and frequency of Mirabegron medication differ from one person to another. It will depend on your medical problem, age, and response to the therapy.

When using this tablet, make sure to read all prescription information and follow all the directions thoroughly. If you are unsure how to use this medicine, talk to your doctor or pharmacist for clarification.

The Myrbetriq doses are as follows:

  • The typical dose for treating adult patients with OAB is 25 mg orally once daily. After four to eight weeks, this intake can be increased, not exceeding the maximum daily dosage of 50 mg.
  • Meanwhile, the recommended dose for the treatment of neurogenic detrusor overactivity for pediatric patients depends on their weight. The oral granules are given to smaller children to ease in swallowing and administration. For a child weighing 11 to 22 kg, the starting dose is 3 mL orally once daily. This can be increased to 6 mL once daily if needed. For a child weighing between 22 kg to 35 kg, the recommended daily dose is 4 mg once daily; this can be increased to 8 mL once daily. For children weighing more than 35 kg, the oral tablet is administered. The starting dose is 25 mg once daily. This dose can be increased to 50 mg once daily after 4–8 weeks.

The following are the directions for administering this medicine:

  • Administer Mirabegron orally once a day
  • The adult can take this medicine with or without regard to food. However, children should take this pill with food.
  • It is best to take this medication whole, with a full glass of water, without chewing, crushing, or breaking it.

Side Effects of Myrbetriq (Mirabegron)

All other medications, including this tablet, may have unwanted side effects that you should not be alarmed about as this is temporary. Myrbetriq side effects may resolve over time after your body has adjusted to the medication.

The following are the Mirabegron side effects that occur most frequently:

  • Headache
  • Common cold symptoms
  • Urinary tract infection
  • Dry mouth
  • Constipation
  • Fast heartbeat
  • Pain or swelling of the nose/throat (nasopharyngitis)

Serious Side Effects

  • Urinary retention (increase your chances of not being able to empty your bladder)
  • High blood pressure

Other Side Effects

Although there are not enough studies that show whether this medicine affects weight and appetite, it is believed that because of urinary retention can lead to temporary weight gain.

Allergic Reactions

  • Angioedema
    • Swelling (face/tongue/throat)
    • Trouble breathing

Note this medication does not increase a patient’s risk for developing dementia, and memory loss is not expected, compared to patients taking anticholinergics who are also used to treat OAB.

Keep in mind that this list does not include all the medical information and health implications related to this medication.

Myrbetriq (Mirabegron) Precaution

Before beginning Myrbetriq medication, make sure to fully disclose your medical history to your doctor, especially if you have the following:

  • High blood pressure
  • Bladder obstruction
  • Trouble emptying the bladder
  • Kidney or Liver disease

Letting your provider know your health conditions will help them decide if this oral medicine is safe for you.

This medicine is contraindicated for patients allergic to Mirabegron and its other ingredients. You should seek medical attention as soon as an allergic reaction occurs.

There are no studies regarding Myrbetriq and pregnancy to inform drug-associated risk outcomes of birth problems or miscarriages. It is best to consult your doctor before administering this tablet. Doing so will help prevent unwanted side effects that can harm you and your baby.

Use caution when drinking alcohol while on Myrbetriq treatment may worsen the side effect of this medication, like dizziness. Apart from this, alcohol can also increase urination, worsening symptoms of OAB.

Take this medicine consistently once a day (depending on your preferred time). Make sure not to discontinue using this medication without consulting your doctor, as it may take four to eight weeks to see improvement in your OAB symptoms.

Keep this medication out of reach of the children and store it safely away from heat, moisture, and direct light.

Myrbetriq Form and Strength

This medicine is available in tablet and granule formulation with the following strengths:

  • Myrbetriq
    • 25 mg Extended-Release tablet
    • 50 mg Extended-Release tablet
  • Myrbetriq Granules

FAQ

When is the best time to take this medication?

It is best to take this medicine at the same time each day, depending on your preferred time.

Is it safe to take this medication for a long time?

Yes, this medicine is meant to be used as a long-term treatment for OAB.

Is this medication safe for children?

Yes, this medication is given to young individuals three years old and above.

How effective is Myrbetriq?

Myrbetriq is a highly potent medication used to treat patients with OAB. It is the treatment of choice of American Urological Association guidelines for OAB.

Additional information

Brand Name:

Myrbetriq

Scientific Name:

Mirabegron

Other Names:

Mirago, Myrbetriq

Strength(s):

25mg, 50mg

Quantities Available:

30, 90

Formulation:

Extended Release Tablet

MedicationsCanada.com receives the above information for Myrbetriq (Mirabegron) from third parties. We provide this information for general informational purposes only, and it is not intended to replace the advice of a physician. Any medical concerns should always be discussed with your doctor or a qualified health care professional.