Doxoteva (Doxorubicin hydrochloride) is a prescription medication used to treat ovarian cancer after the failure of platinum-based chemotherapy. Ovarian cancer occurs when abnormal cells in the ovaries or fallopian tubes grow and multiply out of control. The drug is also used to treat AIDS-related Kaposi’s Sarcoma, metastatic cancers, and many types of cancer. The drug is also combined with bortezomib in patients with multiple myeloma who have received at least one prior therapy or have not previously received bortezomib. The active ingredient in Doxoteva is Doxorubicin hydrochloride. Doxorubicin hydrochloride belongs to a class of drugs called anthracyclines (Antineoplastics). It works by damaging the DNA in cancer cells and interfering with their ability to replicate.
Manufacturer Information
We currently offer the brand Doxoteva from Turkey also called Adrimisin manufactured by Saba in the strength of a 10mg lyophilized powder vial. Unfortunately, the generic Doxorubicin hydrochloride is not available.
Get medical help immediately if you have any signs or an allergic reaction while receiving Doxoteva. The most common side effects of Doxoteva may include the following:
• Appetite loss;
• Diarrhea;
• Eye pain;
• Hair loss;
• Increased thirst;
• Mouth and throat sores;
• Nausea;
• Stomach pain;
• Unusual tiredness or weakness;
• Vomiting;
• Weight gain
Contact your doctor right away if you have any of the severe side effects, including:
• Breathing difficulties;
• Hives;
• Itching;
• Seizures;
• Skin rash;
• Swallowing difficulties
These are not all of the side effects of Doxoteva. Always contact your doctor if you notice any unusual symptoms.
You should not receive Doxoteva if you are allergic to Doxorubicin or any ingredient in Doxoteva. Before you start receiving this medication, tell your doctor about your medical history, especially if you:
• Are about to have any vaccination;
• Are breastfeeding or plan to breastfeed;
• Are pregnant or plan to become pregnant;
• Have an abnormal heart rate;
• Have any heart disease;
• Have had a heart attack;
• Have had radiation therapy to the chest area;
• Have liver disease;
• Have received certain cancer chemotherapy medications
Tell your doctor about all your medications, including prescription, OTC, herbal supplements, and vitamins. Drug interactions between Doxoteva other medications such as verapamil, mitoxantrone, epirubicin, or trastuzumab may occur. Avoid taking Doxorubicin with cyclosporine, progesterone, azathioprine, phenytoin, streptozocin, St. John’s wort, etc. Avoid grapefruit and grapefruit juices when receiving Doxoteva. This medicine may interfere with your menstrual cycle (women) and may stop sperm production (men). However, you should not assume that you cannot get pregnant or that you cannot get someone else pregnant. Tell your doctor if you are pregnant or planning to become pregnant. Doxoteva will harm an unborn baby. Use a reliable birth control method to prevent pregnancy when receiving this medicine. Doxoteva is excreted in breast milk. Inform your doctor if you are breastfeeding or planning to breastfeed. You should not breastfeed while receiving this medication. Doxoteva comes as a powder to be mixed with liquid and injected intravenously. Your doctor will administer this injection once every 21 to 28 days. The length of treatment depends on the type of cancer you have and how well your body responds to the drug. Store Doxoteva at room temperature, away from moisture and heat.
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