Lozide (Indapamide) is used to treat fluid retention (edema) in people with congestive heart failure. Lozide can also be used to treat high blood pressure (hypertension). Lozide belongs to a class of medications called thiazide diuretic (water pill). For the treatment of edema, Lozide works by blocking sodium from being reabsorbed from your urine and into your blood, causing more sodium and water to be secreted from your body. For the treatment of hypertension, it also helps the muscles around the blood vessels throughout your body to relax, allowing the blood to circulate more easily, and lowering the pressure of the blood.

Manufacturer Information

Common side effects of Lozide may include dizziness, weakness, tiredness, back pain, muscle cramps, feeling anxious or agitated, headache, or runny nose.

Contact your doctor immediately if you notice any signs of an electrolyte imbalance, which can include:

• A light-headed feeling, like you might pass out;
• Drowsiness, lack of energy, feeling tired;
• Dry mouth, increased thirst;
• Fast or irregular heartbeats, fluttering in your chest, feeling restless;
• Headache, confusion, slurred speech;
• Leg cramps, muscle weakness or limp feeling;
• Numbness or tingling;
• Severe weakness, loss of coordination, feeling unsteady;
• Vomiting, constipation

This is not a complete list of side effects. If you notice any other side effects not listed here, please contact your doctor or pharmacist.

You should not use Lozide if you are allergic to indapamide, or if you:

• Are allergic to sulfa drugs;
• Are unable to urinate

To make sure this medication is safe for you, tell your doctor if you have ever had cirrhosis or other liver disease, kidney disease, low levels of potassium or sodium in your blood, gout, diabetes, lupus, asthma, thyroid issues, or if you are on a low salt diet. Lozide is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. It is not known if Lozide passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using Lozide. Lozide is not approved for use by anyone younger than 18 years old. While taking this medication, avoid becoming overheated or dehydrated during exercise, in hot weather, or by not drinking enough fluids. Follow your doctors instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough. Lozide may interact with several medications, especially digoxin, digitalis, lithium, blood pressure medication, or steroids (prednisone and other). This is not a complete list of interactions and others may occur. Tell your doctor about any medications, vitamins, or herbal supplements you are currently taking or have recently taken in order to reduce the risk of any possible interactions.

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