Myrbetriq (Mirabegron)

Indications

Myrbetriq (Mirabegron) is a prescription medication used to treat overactive bladders and urinary incontinence. It helps patients relieve their symptoms such as frequent urination and sudden urges to go to the bathroom. It is the first in a new class of drugs that work by selectively activating β3-adrenergic receptors found in the bladder. It works by blocking a certain type of receptor called the muscarinic receptor in the bladder that is involved in OAB symptoms.

It can be used alone or together with other medicines (e.g., solifenacin succinate) to treat the symptoms of an overactive bladder (OAB), such as incontinence (loss of bladder control), a strong need to urinate right away, or a frequent need to urinate.

Myrbetriq is available in two strength 25 mg and 50 mg tablet both taken by mouth. These forms are both extended releases, meaning the medication is slowly released into the body over time after taking a dose.

Uses and Dosage

Patients should take Myrbetriq strictly according to the instructions of a physician or healthcare professional. It is important to swallow the tablets whole with a full glass of water; crushing or chewing the tablets may reduce the effectiveness of the medication.

The recommended starting dose of Myrbetriq (mirabegron) is 25 mg taken orally once daily, either with or without food. However, children must take Myrbetriq with food. Generally, efficacy can be expected within 8 weeks of treatment, and the dose may be increased to 50 mg once daily if necessary. It is important to take Myrbetriq exactly as prescribed and to swallow the tablets whole; do not crush, divide, or chew the tablets.

Side effect

Common Side Effect of Mirabegron May Includes

• Bladder pain
• Bloody or cloudy urine
• Difficult, burning, or painful urination
• Dizziness
• Frequent urge to urinate
• Headache
• Lower back or side pain
• Nervousness
• Pounding in the ears
• Slow, fast, or irregular heartbeat

Serious Side Effects of Myrbetriq

• Blurred vision
• Fast or pounding heartbeats
• High blood pressure
• Pain or burning when you urinate
• Painful or difficult urination
• Pounding in your neck or ears
• Severe headache
• Trouble emptying your bladder

Form and strength

Myrbetriq and its generic alternative Mirabegron available in the following forms and strength:

Myrbetriq: Extended-Release Tablet

• 25 mg
• 50 mg

Mirabegron: Extended-Release Tablet

• 25 mg
• 50 mg

Caution

Possible cautions of Myrbetriq include:

• It should not be used in patients with moderate or severe hepatic impairment.
• It should not be used in patients with severe renal impairment or end stage renal disease.
• It should not be used in patients with uncontrolled hypertension.
• It should not be used in patients with a history of urinary retention.
• It should not be used in patients with certain conditions such as narrow-angle glaucoma.
• It should not be used in patients with known hypersensitivity to Myrbetriq or any of its ingredients.
• It should not be used in patients taking a monoamine oxidase inhibitor (MAOI).
• It should not be used in pregnant women unless the potential benefit to the mother outweighs the potential risk to the fetus.
• It should not be used in nursing mothers unless the potential benefit to the mother outweighs the potential risk to the infant.

Frequently Asked Questions (FAQ)

Some Frequently Asked Questions (FAQs) about Myrbetriq (mirabegron) include:

What is Myrbetriq used for?

Myrbetriq is used to treat overactive bladder (OAB) with symptoms of frequent urination, urgency, and urgent incontinence.

What is the recommended starting dose of Myrbetriq?

The recommended starting dose of Myrbetriq is 25 mg taken orally once daily, either with or without food. However, children must take Myrbetriq with food.

Can Myrbetriq be split, crushed, or chewed?

No, Myrbetriq should be swallowed whole and should not be split, crushed, or chewed. Doing so may release the active ingredients all at once and increase the risk of adverse effects.

How long does it take for Myrbetriq to start working?

Myrbetriq usually starts to work within a few days of taking it. However, it can take up to 8 weeks for Myrbetriq to reach its full effect.

Is Myrbetriq safe to take?

Myrbetriq is generally safe to take, and it has been studied in clinical trials. However, like all medications, it can cause side effects in some people. Talk to your doctor if you are concerned about taking Myrbetriq.

Resources

• https://www.mayoclinic.org/drugs-supplements/mirabegron-oral-route/side-effects/drg-20075675
• https://www.rxlist.com/myrbetriq-side-effects-drug-center.htm
• https://www.webmd.com/drugs/2/drug-162243-1495/myrbetriq-oral/mirabegron-extended-release-oral/details
• https://www.healthline.com/health/drugs/myrbetriq#side-effects