Food and Drug Administration (FDA) has announced that they discovered a nitrosamine impurity N-Nitrosodimethylamine (NDMA) which exceeded the acceptable limit in tested lots of Metformin extended-release. The FDA has reached out to five firms to recommend a voluntary recall. Stay updated on FDA recalls here. According to the FDA “patients should continue taking metformin tablets even after recalls occur, until they consult with their health care professional who can prescribe a replacement.”Health Canada, the UK Medical Health Products Regulatory, and the European Medicines Agency Administration have previously provided information on NDMA impurities with metformin. You can stay updated below:
Metformin (Brand name: Glucophage) is a generic medication prescribed for the treatment of type 2 diabetes. This drug works by aiding in restoration of the body's response to insulin. Metformin decreases the amount of sugar your liver makes. Along with diet and exercise, generic metformin helps you take control of your diabetes. It may also lessen patients’ risk of heart attack and/or stroke. Generic metformin in the U.S. can often be purchased at lower cost than in Canada and other international pharmacies. People can save money on metformin 500 mg by comparing metformin prices at Canadian and international online pharmacies with discount prices available at U.S. pharmacies. Most of the metformin sold in the U.S. is manufactured in India.
The total price includes shipping fees which typically cover an entire order, making it more economical to purchase multiple medications in the same order.
U.S. government officials have stated that individuals who order non-controlled prescription drugs from Canada or other foreign sources (up to a three-month supply) for their own use are not being pursued or prosecuted - although it is technically not legal for individuals to import most prescription drugs. The U.S FDA regulates the safety and efficacy of medications sold in U.S. pharmacies. Medications dispensed from outside the U.S. are regulated for safety and efficacy by pharmaceutical/pharmacy regulatory authorities in other countries. Read how regulations may differ by country.