Entresto (Sacubitril/Valsartan)
Medication information written by Dr. Conner Sheehy, PharmD, BCPS
Updated - May 3, 2024
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Entresto (Sacubitril/Valsartan) – Product Information
Entresto is a prescription medication that is used to lessen the risk of cardiovascular death. People taking it are not highly likely to get hospitalized for Class II and Class IV heart failure.
To buy Entresto online, connect with our PricePro Pharmacy team by the phone or our live online chat. You can also check out our reviews to see how we have helped over thousands of patients find safe and affordable medication.
This medication is manufactured by Novartis, and we carry it in these dosages: 24mg/26mg, 49mg/51mg and 97mg/103mg. There are two active medicinal ingredients are sacubitril and valsartan. We offer this medication from both Canada and the United Kingdom. The shipping time would be 7 to 10 business days from when the dispensing pharmacy fills the order.
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Learn More About Ordering Entresto With Us
Patients use Entresto to mitigate the risk of cardiovascular death. Those who take this medication as prescribed are less likely to experience Class II and Class IV heart failure. Purchasing this medication through conventional pharmacies can lead to financial strain, though. You can save time and money by ordering your Entresto prescription through PricePro Pharmacy.
Placing Your Order
Reach the PricePro Pharmacy Team via phone or live online chat to start. They can handle questions and concerns you may have. You can also explore our past customer reviews to gain insight into Entresto information and what you can expect when ordering. You'll learn that we've helped thousands of customers like you find safe and affordable medication.
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Generic Entresto
At this time, there is only once generic version for Entresto available for ordering. Should more become available, we'll add it to our site as soon as possible.
This will allow you to save even more money on your prescription. We will also notify our customers when we stock new medications, providing access to affordable medication as soon as possible.
Price Matching
If you've found Ernesto available at another accredited pharmacy for a cheaper price, we'll happily match or beat it. However, it's important to note that the other pharmacy needs to have the medication in stock to take advantage of our price matching.
Take Advantage of Low Entresto Costs
The Canadian government constantly monitors medication prices to keep them affordable. This is one of the many reasons PricePro Pharmacy is an amazing option for those who require prescription medication.
Keep in mind that there aren't notable differences between our medications and the more expensive options available. The only discrepancy you'll notice is paying far less money to fulfill your prescription.
Answers to Common Questions
Is a Patient Assistance Program Available?
Under the right circumstances, uninsured patients can use a Patient Assistance Program through Novartis to reduce the amount they owe for their medication. In some situations, this could reduce the cost down to $0.00.
What If I'm Taking Other Medicine?
It's best to consult your doctor if you're taking any other medication. They'll advise you on how to avoid potential complications.
How Do I Use Entresto?
Take one tablet (with or without food) in the morning and evening. The strength of your dosage will vary depending on your prescription.
Place Your Entresto Order Today
Our professional team at PricePro Pharmacy is ready to assist you with order placement. You can get started by creating your online account and uploading your Entresto prescription today.
Entresto (Sacubitril and Valsartan) Medication Information
Uses
Entresto contains the medications valsartan and sacubitril. It is prescribed for people with heart failure and reduces the risk of death and hospitalization from cardiac events like heart attack and stroke. If you use Entresto, you should be taking it with other heart medications prescribed by your doctor.
The first active ingredient is sacubitril, which is a neprilysin inhibitor. Neprilysin breaks down certain protein molecules in the kidneys, and these molecules help protect the kidneys and heart.
The second active ingredient is valsartan, an angiotensin II receptor blocker (ARB) that is used to treat high blood pressure when prescribed on its own. In combination with sacubitril, valsartan works in heart failure by decreasing the stress on the heart.
Dosage
Entresto comes in the following dosage forms:
- Sacubitril/Valsartan 24/26 mg
- Sacubitril/Valsartan 49/51 mg
- Sacubitril/Valsartan 93/103 mg
The normal starting dose is one tablet of Entresto 24/26 mg by mouth twice daily. After two to four weeks, the dose may be increased to Entresto 49/51 mg by mouth twice daily. After another two to four weeks, the dose may be increased again to Entresto 97/103 mg twice daily.
Take Entresto with or without food.
Side Effects
- Cough
- Decreased hematocrit
- Decreased hemoglobin
- Dizziness
- Dizziness
- High blood potassium
- Increase blood creatinine
- Kidney failure
- Low blood pressure
Precautions
If you were taking an ACE inhibitor before starting Entresto, you should stop the ACE inhibitor and wait at least 36 hours before starting Entresto. Examples of ACE inhibitors include:
- Benazepril
- Captopril
- Enalapril
- Fosinopril
- Lisinopril
- Quinapril
- Ramipril
If you have diabetes, do not take Tekturna (aliskiren) and Entresto together.
If you have taken an ACE inhibitor or ARB in the past and experienced swelling under the skin, you should not take Entresto.
Interactions
Common drug interactions with Entresto may include:
- ACE inhibitors
- Aliskiren
- Aspirin
- Eplerenone
- Ibuprofen
- Lithium
- Naproxen
- Sodium phosphates
- Spironolactone
Storage
Store Entresto at controlled room temperature between 20°C to 25°C (77°F). Keep Entresto out of rooms with high moisture like the bathroom or kitchen.
Pharmacist Tips
- Take Entresto twice daily with or without food.
- Entresto is harmful to a developing fetus. If you are taking Entresto, tell your doctor immediately.
- If you miss a dose of Entresto, take it as soon as you remember if it’s within eight hours. If it’s later than eight hours, do not double up, and take your next dose at the regular time.
Entresto FAQs
Can I take Entresto if I have impaired kidney function?
Yes, in most cases, but it depends on your kidney function. Speak with your doctor about your current kidney function and whether you can continue Entresto or if you should lower the dose.
How long do I need to take Entresto?
It should be taken lifelong unless directed by your doctor.
What should I do if I get dizzy while taking Entresto?
Dizziness may be a sign of low blood pressure. Sit or stand slowly and take your blood pressure as soon as you have the chance.
Related Products
References
- Entresto [package insert]. East Hanover, NJ: Novartis; 2019.
Author: Dr. Conor Sheehy, PharmD, BCPS
Dr. Sheehy is a board-certified pharmacotherapy specialist. He has worked in multiple practice settings, including retail and hospital pharmacies, and in medical clinics. He specializes in anticoagulation, psychiatric medications, and diabetes medications. He strives to empower his patients to understand their medications and improve their overall medical care.
The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.
